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Particle physics experiments such as those run in the Large Hadron Collider result in huge quantities of data, which are boiled down to a few numbers from which it is hoped that a signal will be detected. We discuss a simple probability model for this and derive frequentist and noninformative Bayesian procedures for inference about the signal. Both are highly accurate in realistic cases, with the frequentist procedure having the edge for interval estimation, and the Bayesian procedure yielding slightly better point estimates. We also argue that the significance, or $p$-value, function based on the modified likelihood root provides a comprehensive presentation of the information in the data and should be used for inference.
Spatial prediction of weather-elements like temperature, precipitation, and barometric pressure are generally based on satellite imagery or data collected at ground-stations. None of these data provide information at a more granular or hyper-local re
In this article we derive an unbiased expression for the expected mean-squared error associated with continuously differentiable estimators of the noncentrality parameter of a chi-square random variable. We then consider the task of denoising squared
How should social scientists understand and communicate the uncertainty of statistically estimated causal effects? It is well-known that the conventional significance-vs.-insignificance approach is associated with misunderstandings and misuses. Behav
The determination of the infection fatality rate (IFR) for the novel SARS-CoV-2 coronavirus is a key aim for many of the field studies that are currently being undertaken in response to the pandemic. The IFR together with the basic reproduction numbe
Cryo-electron microscopy (cryo-EM) is an emerging experimental method to characterize the structure of large biomolecular assemblies. Single particle cryo-EM records 2D images (so-called micrographs) of projections of the three-dimensional particle,