Swift has initiated a new era of understanding the extremes of active galactic nuclei (AGN) variability, their drivers and underlying physics. This is based on its rapid response, high sensitivity, good spatial resolution, and its ability to collect
simultaneously X--ray-to-optical SEDs. Here, we present results from our recent monitoring campaigns with Swift of highly variable AGN, including outbursts, deep low states, and unusual long-term trends in several Seyfert galaxies including Mrk 335, WPVS007, and RXJ2314.9+2243. We also report detection of a new X-ray and optical outburst of IC 3599 and our Swift follow-ups. IC 3599 was previously known as one of the AGN with the highest-amplitude outbursts. We briefly discuss implications of this second outburst of IC 3599 for emission scenarios including accretion-disk variability, repeat tidal disruption events, and the presence of a binary supermassive black hole.
