Locating lesions is important in the computer-aided diagnosis of X-ray images. However, box-level annotation is time-consuming and laborious. How to locate lesions accurately with few, or even without careful annotations is an urgent problem. Althoug
h several works have approached this problem with weakly-supervised methods, the performance needs to be improved. One obstacle is that general weakly-supervised methods have failed to consider the characteristics of X-ray images, such as the highly-structural attribute. We therefore propose the Cross-chest Graph (CCG), which improves the performance of automatic lesion detection by imitating doctors training and decision-making process. CCG models the intra-image relationship between different anatomical areas by leveraging the structural information to simulate the doctors habit of observing different areas. Meanwhile, the relationship between any pair of images is modeled by a knowledge-reasoning module to simulate the doctors habit of comparing multiple images. We integrate intra-image and inter-image information into a unified end-to-end framework. Experimental results on the NIH Chest-14 database (112,120 frontal-view X-ray images with 14 diseases) demonstrate that the proposed method achieves state-of-the-art performance in weakly-supervised localization of lesions by absorbing professional knowledge in the medical field.
Identifying and locating diseases in chest X-rays are very challenging, due to the low visual contrast between normal and abnormal regions, and distortions caused by other overlapping tissues. An interesting phenomenon is that there exist many simila
r structures in the left and right parts of the chest, such as ribs, lung fields and bronchial tubes. This kind of similarities can be used to identify diseases in chest X-rays, according to the experience of broad-certificated radiologists. Aimed at improving the performance of existing detection methods, we propose a deep end-to-end module to exploit the contralateral context information for enhancing feature representations of disease proposals. First of all, under the guidance of the spine line, the spatial transformer network is employed to extract local contralateral patches, which can provide valuable context information for disease proposals. Then, we build up a specific module, based on both additive and subtractive operations, to fuse the features of the disease proposal and the contralateral patch. Our method can be integrated into both fully and weakly supervised disease detection frameworks. It achieves 33.17 AP50 on a carefully annotated private chest X-ray dataset which contains 31,000 images. Experiments on the NIH chest X-ray dataset indicate that our method achieves state-of-the-art performance in weakly-supervised disease localization.
Most of convolutional neural networks share the same characteristic: each convolutional layer is followed by a nonlinear activation layer where Rectified Linear Unit (ReLU) is the most widely used. In this paper, we argue that the designed structure
with the equal ratio between these two layers may not be the best choice since it could result in the poor generalization ability. Thus, we try to investigate a more suitable method on using ReLU to explore the better network architectures. Specifically, we propose a proportional module to keep the ratio between convolution and ReLU amount to be N:M (N>M). The proportional module can be applied in almost all networks with no extra computational cost to improve the performance. Comprehensive experimental results indicate that the proposed method achieves better performance on different benchmarks with different network architectures, thus verify the superiority of our work.
