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Research in media forensics has gained traction to combat the spread of misinformation. However, most of this research has been directed towards content generated on social media. Biomedical image forensics is a related problem, where manipulation or misuse of images reported in biomedical research documents is of serious concern. The problem has failed to gain momentum beyond an academic discussion due to an absence of benchmark datasets and standardized tasks. In this paper we present BioFors -- the first dataset for benchmarking common biomedical image manipulations. BioFors comprises 47,805 images extracted from 1,031 open-source research papers. Images in BioFors are divided into four categories -- Microscopy, Blot/Gel, FACS and Macroscopy. We also propose three tasks for forensic analysis -- external duplication detection, internal duplication detection and cut/sharp-transition detection. We benchmark BioFors on all tasks with suitable state-of-the-art algorithms. Our results and analysis show that existing algorithms developed on common computer vision datasets are not robust when applied to biomedical images, validating that more research is required to address the unique challenges of biomedical image forensics.
Unlike conventional zero-shot classification, zero-shot semantic segmentation predicts a class label at the pixel level instead of the image level. When solving zero-shot semantic segmentation problems, the need for pixel-level prediction with surrou nding context motivates us to incorporate spatial information using positional encoding. We improve standard positional encoding by introducing the concept of Relative Positional Encoding, which integrates spatial information at the feature level and can handle arbitrary image sizes. Furthermore, while self-training is widely used in zero-shot semantic segmentation to generate pseudo-labels, we propose a new knowledge-distillation-inspired self-training strategy, namely Annealed Self-Training, which can automatically assign different importance to pseudo-labels to improve performance. We systematically study the proposed Relative Positional Encoding and Annealed Self-Training in a comprehensive experimental evaluation, and our empirical results confirm the effectiveness of our method on three benchmark datasets.
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