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120 - Shaode Yu , Haobo Chen , Hang Yu 2020
Feature selection is important in data representation and intelligent diagnosis. Elastic net is one of the most widely used feature selectors. However, the features selected are dependant on the training data, and their weights dedicated for regulari zed regression are irrelevant to their importance if used for feature ranking, that degrades the model interpretability and extension. In this study, an intuitive idea is put at the end of multiple times of data splitting and elastic net based feature selection. It concerns the frequency of selected features and uses the frequency as an indicator of feature importance. After features are sorted according to their frequency, linear support vector machine performs the classification in an incremental manner. At last, a compact subset of discriminative features is selected by comparing the prediction performance. Experimental results on breast cancer data sets (BCDR-F03, WDBC, GSE 10810, and GSE 15852) suggest that the proposed framework achieves competitive or superior performance to elastic net and with consistent selection of fewer features. How to further enhance its consistency on high-dimension small-sample-size data sets should be paid more attention in our future work. The proposed framework is accessible online (https://github.com/NicoYuCN/elasticnetFR).
Computed Tomography (CT) is an advanced imaging technology used in many important applications. Here we present a deep-learning (DL) based CT super-resolution (SR) method that can reconstruct low-resolution (LR) sinograms into high resolution (HR) CT images. The method synergistically combines a SR model in sinogram domain, a deblur model in image domain, and the iterative framework into a CT SR algorithm super resolution and deblur based iterative reconstruction (SADIR). We incorporated the CT domain knowledge into the SADIR and unrolled it into a DL network (SADIR Net). The SADIR Net is a zero shot learning (ZSL) network, which can be trained and tested with a single sinogram in the test time. The SADIR was evaluated via SR CT imaging of a Catphan700 physical phantom and a biological ham, and its performance was compared to the other state of the art (SotA) DL-based methods. The results show that the zero-shot SADIR-Net can indeed provide a performance comparable to the other SotA methods for CT SR reconstruction, especially in situations where training data is limited. The SADIR method can find use in improving CT resolution beyond hardware limits or lowering requirement on CT hardware.
More attention is being paid for feature importance ranking (FIR), in particular when thousands of features can be extracted for intelligent diagnosis and personalized medicine. A large number of FIR approaches have been proposed, while few are integ rated for comparison and real-life applications. In this study, a matlab toolbox is presented and a total of 30 algorithms are collected. Moreover, the toolbox is evaluated on a database of 163 ultrasound images. To each breast mass lesion, 15 features are extracted. To figure out the optimal subset of features for classification, all combinations of features are tested and linear support vector machine is used for the malignancy prediction of lesions annotated in ultrasound images. At last, the effectiveness of FIR is analyzed according to performance comparison. The toolbox is online (https://github.com/NicoYuCN/matFIR). In our future work, more FIR methods, feature selection methods and machine learning classifiers will be integrated.
Many interpolation methods have been developed for high visual quality, but fail for inability to preserve image structures. Edges carry heavy structural information for detection, determination and classification. Edge-adaptive interpolation approac hes become a center of focus. In this paper, performance of four edge-directed interpolation methods comparing with two traditional methods is evaluated on two groups of images. These methods include new edge-directed interpolation (NEDI), edge-guided image interpolation (EGII), iterative curvature-based interpolation (ICBI), directional cubic convolution interpolation (DCCI) and two traditional approaches, bi-linear and bi-cubic. Meanwhile, no parameters are mentioned to measure edge-preserving ability of edge-adaptive interpolation approaches and we proposed two. One evaluates accuracy and the other measures robustness of edge-preservation ability. Performance evaluation is based on six parameters. Objective assessment and visual analysis are illustrated and conclusions are drawn from theoretical backgrounds and practical results.
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