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Relic abundance of asymmetric Dark Matter particles in brane world cosmological scenario is investigated in this article. Hubble expansion rate is enhanced in brane world cosmology and it affects the relic abundance of asymmetric Dark Matter particle s. We analyze how the relic abundance of asymmetric Dark Matter is changed in this model. We show that in such kind of nonstandard cosmological scenario, indirect detection of asymmetric Dark Matter is possible if the cross section is small enough which let the anti--particle abundance kept in the same amount with the particle. We show the indirect detection signal constraints can be used to such model only when the cross section and the 5 dimensional Planck mass scale are in appropriate values.
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