Gauge theories living on stacks of D7-branes are holographically related to IIB gravitational backgrounds with a varying axion-dilaton field (F-theory). The axion-dilaton field is generated by D7, O7 and D-instanton sources and can be written in term
s of the chiral correlators of the eight dimensional gauge theory living on the D7-branes. Using localization techniques, we prove that the same correlators determine the gauge coupling of the four-dimensional N=2 supersymmetric SU(2) gauge theories living on the elementary D3-brane which probes the F-theory geometries.
