Zero degree measurements of 12C fragmentation at 95 MeV/nucleon on thin targets

During therapeutic treatments using ions such as carbon, nuclear interactions between the incident ions and nuclei present in organic tissues may occur, leading to the attenuation of the incident beam intensity and to the production of secondary light charged particles. As the biological dose deposited in the tumor and the surrounding healthy tissues depends on the beam composition, an accurate knowledge of the fragmentation processes is thus essential. In particular, the nuclear interaction models have to be validated using experimental double differential cross sections which are still very scarce. An experiment was realized in 2011 at GANIL to obtain these cross sections for a 95 MeV/nucleon carbon beam on different thin targets for angles raging from 4 to 43{deg} . In order to complete these data, a new experiment was performed on September 2013 at GANIL to measure the fragmentation cross section at zero degree for a 95 MeV/nucleon carbon beam on thin targets. In this work, the experimental setup will be described, the analysis method detailed and the results presented.

Benchmarking GEANT4 nuclear models for hadron therapy with 95 MeV/nucleon carbon ions

In carbon-therapy, the interaction of the incoming beam with human tissues may lead to the production of a large amount of nuclear fragments and secondary light particles. An accurate estimation of the biological dose deposited into the tumor and the surrounding healthy tissues thus requires sophisticated simulation tools based on nuclear reaction models. The validity of such models requires intensive comparisons with as many sets of experimental data as possible. Up to now, a rather limited set of double di erential carbon fragmentation cross sections have been measured in the energy range used in hadrontherapy (up to 400 MeV/A). However, new data have been recently obtained at intermediate energy (95 MeV/A). The aim of this work is to compare the reaction models embedded in the GEANT4 Monte Carlo toolkit with these new data. The strengths and weaknesses of each tested model, i.e. G4BinaryLightIonReaction, G4QMDReaction and INCL++, coupled to two di fferent de-excitation models, i.e. the generalized evaporation model and the Fermi break-up are discussed.