Based on our analysis of the contributions from the connected and disconnected contraction diagrams to the pion-kaon scattering amplitude, we provide the first determination of the low-energy constant $L_0^r$ in SU$(4|1)$ Partially-Quenched Chiral Pe
rturbation Theory from data of the Extended Twisted Mass Collaboration, $L_0^r = 0.51(26)cdot 10^{-3}$ at $mu=1$ GeV.
We study the contributions from the connected and disconnected contraction diagrams to the pion-kaon scattering amplitude within the framework of SU$(4|1)$ partially-quenched chiral perturbation theory. Combining this with a finite-volume analysis, w
e demonstrate that a lattice calculation of the easier computable connected correlation functions is able to provide valuable information of the noisier disconnected correlation functions, and may serve as a theory guidance for the future refinement of the corresponding lattice techniques.
