Laser-driven ions have compelling properties and their potential use for medical applications has attracted a huge global interest. One of the major challenges of these applications is generating beams of the required energies. To date, there has bee
n no systematic study of the effect of laser intensity on the generation of laser-driven ions from ultrathin foils during relativistic transparency. Here we present a scaling for ion energies with respect to the on-target laser intensity and in considering target thickness we find an optimum thickness closely related to the experimentally observed relativistic transparency. A steep linear scaling with the normalized laser amplitude a0 has been measured and verified with PIC simulations. In contrast to TNSA, this scaling is much steeper and has been measured for ions with Z > 1. Following our results, ion energies exceeding 100MeV/amu are already accessible with currently available laser systems enabling realization of numerous advanced applications
Proton (and ion) cancer therapy has proven to be an extremely effective even supe-rior method of treatment for some tumors 1-4. A major problem, however, lies in the cost of the particle accelerator facilities; high procurement costs severely limit t
he availability of ion radiation therapy, with only ~26 centers worldwide. Moreover, high operating costs often prevent economic operation without state subsidies and have led to a shutdown of existing facilities 5,6. Laser-accelerated proton and ion beams have long been thought of as a way out of this dilemma, with the potential to provide the required ion beams at lower cost and smaller facility footprint 7-14. The biggest challenge has been the achievement of sufficient particle energy for therapy, in the 150-250 MeV range for protons 15,16. For the last decade, the maximum exper-imentally observed energy of laser-accelerated protons has remained at ~60 MeV 17. Here we the experimental demonstration of laser-accelerated protons to energies exceeding 150 MeV, reaching the therapy window. This was achieved through a dif-ferent acceleration regime rather than a larger laser, specifically a 150 TW laser with CH2 nano-targets in the relativistically transparent regime 18,19. We also demonstrate a clear scaling law with laser intensity based on analytical theory, computer simulations and experimental validation that will enable design of a pro-totype system spanning the full range of therapeutically desirable energies.
Stimulated Raman scattering (SRS) in its strongly nonlinear, kinetic regime is controlled by a technique of deterministic, strong temporal modulation and spatial scrambling of laser speckle patterns, called Spike Trains of Uneven Duration and Delay (
STUD pulses) [B. Afeyan and S. Huller, Phys. Rev. Lett. (submitted)]. Kinetic simulations show that use of STUD pulses may decrease SRS reflectivity by more than an order of magnitude over random-phase-plate (RPP) or induced-spatial-incoherence (ISI) beams of the same average intensity and comparable bandwidth.
