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Medical Code Assignment with Gated Convolution and Note-Code Interaction

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 Added by Shaoxiong Ji
 Publication date 2020
and research's language is English




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Medical code assignment from clinical text is a fundamental task in clinical information system management. As medical notes are typically lengthy and the medical coding systems code space is large, this task is a long-standing challenge. Recent work applies deep neural network models to encode the medical notes and assign medical codes to clinical documents. However, these methods are still ineffective as they do not fully encode and capture the lengthy and rich semantic information of medical notes nor explicitly exploit the interactions between the notes and codes. We propose a novel method, gated convolutional neural networks, and a note-code interaction (GatedCNN-NCI), for automatic medical code assignment to overcome these challenges. Our methods capture the rich semantic information of the lengthy clinical text for better representation by utilizing embedding injection and gated information propagation in the medical note encoding module. With a novel note-code interaction design and a graph message passing mechanism, we explicitly capture the underlying dependency between notes and codes, enabling effective code prediction. A weight sharing scheme is further designed to decrease the number of trainable parameters. Empirical experiments on real-world clinical datasets show that our proposed model outperforms state-of-the-art models in most cases, and our model size is on par with light-weighted baselines.

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Medical code assignment, which predicts medical codes from clinical texts, is a fundamental task of intelligent medical information systems. The emergence of deep models in natural language processing has boosted the development of automatic assignment methods. However, recent advanced neural architectures with flat convolutions or multi-channel feature concatenation ignore the sequential causal constraint within a text sequence and may not learn meaningful clinical text representations, especially for lengthy clinical notes with long-term sequential dependency. This paper proposes a Dilated Convolutional Attention Network (DCAN), integrating dilated convolutions, residual connections, and label attention, for medical code assignment. It adopts dilated convolutions to capture complex medical patterns with a receptive field which increases exponentially with dilation size. Experiments on a real-world clinical dataset empirically show that our model improves the state of the art.
Unsupervised pretraining is an integral part of many natural language processing systems, and transfer learning with language models has achieved remarkable results in many downstream tasks. In the clinical application of medical code assignment, diagnosis and procedure codes are inferred from lengthy clinical notes such as hospital discharge summaries. However, it is not clear if pretrained models are useful for medical code prediction without further architecture engineering. This paper conducts a comprehensive quantitative analysis of various contextualized language models performance, pretrained in different domains, for medical code assignment from clinical notes. We propose a hierarchical fine-tuning architecture to capture interactions between distant words and adopt label-wise attention to exploit label information. Contrary to current trends, we demonstrate that a carefully trained classical CNN outperforms attention-based models on a MIMIC-III subset with frequent codes. Our empirical findings suggest directions for improving the medical code assignment application.
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