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An inverse problem involving a viscous Eikonal equation with applications in electrophysiology

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 Added by Philip Trautmann
 Publication date 2020
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and research's language is English




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In this work we discuss the reconstruction of cardiac activation instants based on a viscous Eikonal equation from boundary observations. The problem is formulated as an least squares problem and solved by a projected version of the Levenberg Marquardt method. Moreover, we analyze the wellposeness of the state equation and derive the gradient of the least squares functional with respect to the activation instants. In the numerical examples we also conduct an experiment in which the location of the activation sites and the activation instants are reconstructed jointly based on an adapted version of the shape gradient method from https://link.springer.com/article/10.1007/s00285-019-01419-3. We are able to reconstruct the activation instants as well as the locations of the activations with high accuracy relative to the noise level.

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