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Register a new userFetusMap: Fetal Pose Estimation in 3D Ultrasound
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Added by
Haoran Dou
Publication date
2019
fields
Informatics Engineering
and research's language is
English
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The 3D ultrasound (US) entrance inspires a multitude of automated prenatal examinations. However, studies about the structuralized description of the whole fetus in 3D US are still rare. In this paper, we propose to estimate the 3D pose of fetus in US volumes to facilitate its quantitative analyses in global and local scales. Given the great challenges in 3D US, including the high volume dimension, poor image quality, symmetric ambiguity in anatomical structures and large variations of fetal pose, our contribution is three-fold. (i) This is the first work about 3D pose estimation of fetus in the literature. We aim to extract the skeleton of whole fetus and assign different segments/joints with correct torso/limb labels. (ii) We propose a self-supervised learning (SSL) framework to finetune the deep network to form visually plausible pose predictions. Specifically, we leverage the landmark-based registration to effectively encode case-adaptive anatomical priors and generate evolving label proxy for supervision. (iii) To enable our 3D network perceive better contextual cues with higher resolution input under limited computing resource, we further adopt the gradient check-pointing (GCP) strategy to save GPU memory and improve the prediction. Extensively validated on a large 3D US dataset, our method tackles varying fetal poses and achieves promising results. 3D pose estimation of fetus has potentials in serving as a map to provide navigation for many advanced studies.
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In this paper, we propose an adaptive weighting regression (AWR) method to leverage the advantages of both detection-based and regression-based methods. Hand joint coordinates are estimated as discrete integration of all pixels in dense representation, guided by adaptive weight maps. This learnable aggregation process introduces both dense and joint supervision that allows end-to-end training and brings adaptability to weight maps, making the network more accurate and robust. Comprehensive exploration experiments are conducted to validate the effectiveness and generality of AWR under various experimental settings, especially its usefulness for different types of dense representation and input modality. Our method outperforms other state-of-the-art methods on four publicly available datasets, including NYU, ICVL, MSRA and HANDS 2017 dataset.
Fetal brain magnetic resonance imaging (MRI) offers exquisite images of the developing brain but is not suitable for anomaly screening. For this ultrasound (US) is employed. While expert sonographers are adept at reading US images, MR images are much easier for non-experts to interpret. Hence in this paper we seek to produce images with MRI-like appearance directly from clinical US images. Our own clinical motivation is to seek a way to communicate US findings to patients or clinical professionals unfamiliar with US, but in medical image analysis such a capability is potentially useful, for instance, for US-MRI registration or fusion. Our model is self-supervised and end-to-end trainable. Specifically, based on an assumption that the US and MRI data share a similar anatomical latent space, we first utilise an extractor to determine shared latent features, which are then used for data synthesis. Since paired data was unavailable for our study (and rare in practice), we propose to enforce the distributions to be similar instead of employing pixel-wise constraints, by adversarial learning in both the image domain and latent space. Furthermore, we propose an adversarial structural constraint to regularise the anatomical structures between the two modalities during the synthesis. A cross-modal attention scheme is proposed to leverage non-local spatial correlations. The feasibility of the approach to produce realistic looking MR images is demonstrated quantitatively and with a qualitative evaluation compared to real fetal MR images.
End-to-end deep representation learning has achieved remarkable accuracy for monocular 3D human pose estimation, yet these models may fail for unseen poses with limited and fixed training data. This paper proposes a novel data augmentation method that: (1) is scalable for synthesizing massive amount of training data (over 8 million valid 3D human poses with corresponding 2D projections) for training 2D-to-3D networks, (2) can effectively reduce dataset bias. Our method evolves a limited dataset to synthesize unseen 3D human skeletons based on a hierarchical human representation and heuristics inspired by prior knowledge. Extensive experiments show that our approach not only achieves state-of-the-art accuracy on the largest public benchmark, but also generalizes significantly better to unseen and rare poses. Code, pre-trained models and tools are available at this HTTPS URL.
Detecting acoustic shadows in ultrasound images is important in many clinical and engineering applications. Real-time feedback of acoustic shadows can guide sonographers to a standardized diagnostic viewing plane with minimal artifacts and can provide additional information for other automatic image analysis algorithms. However, automatically detecting shadow regions using learning-based algorithms is challenging because pixel-wise ground truth annotation of acoustic shadows is subjective and time consuming. In this paper we propose a weakly supervised method for automatic confidence estimation of acoustic shadow regions. Our method is able to generate a dense shadow-focused confidence map. In our method, a shadow-seg module is built to learn general shadow features for shadow segmentation, based on global image-level annotations as well as a small number of coarse pixel-wise shadow annotations. A transfer function is introduced to extend the obtained binary shadow segmentation to a reference confidence map. Additionally, a confidence estimation network is proposed to learn the mapping between input images and the reference confidence maps. This network is able to predict shadow confidence maps directly from input images during inference. We use evaluation metrics such as DICE, inter-class correlation and etc. to verify the effectiveness of our method. Our method is more consistent than human annotation, and outperforms the state-of-the-art quantitatively in shadow segmentation and qualitatively in confidence estimation of shadow regions. We further demonstrate the applicability of our method by integrating shadow confidence maps into tasks such as ultrasound image classification, multi-view image fusion and automated biometric measurements.
We propose a Bayesian approximation to a deep learning architecture for 3D hand pose estimation. Through this framework, we explore and analyse the two types of uncertainties that are influenced either by data or by the learning capability. Furthermore, we draw comparisons against the standard estimator over three popular benchmarks. The first contribution lies in outperforming the baseline while in the second part we address the active learning application. We also show that with a newly proposed acquisition function, our Bayesian 3D hand pose estimator obtains lowest errors with the least amount of data. The underlying code is publicly available at https://github.com/razvancaramalau/al_bhpe.
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