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Register a new userSelf-Attention Equipped Graph Convolutions for Disease Prediction
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Anees Kazi
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Multi-modal data comprising imaging (MRI, fMRI, PET, etc.) and non-imaging (clinical test, demographics, etc.) data can be collected together and used for disease prediction. Such diverse data gives complementary information about the patients condition to make an informed diagnosis. A model capable of leveraging the individuality of each multi-modal data is required for better disease prediction. We propose a graph convolution based deep model which takes into account the distinctiveness of each element of the multi-modal data. We incorporate a novel self-attention layer, which weights every element of the demographic data by exploring its relation to the underlying disease. We demonstrate the superiority of our developed technique in terms of computational speed and performance when compared to state-of-the-art methods. Our method outperforms other methods with a significant margin.
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Brain networks have received considerable attention given the critical significance for understanding human brain organization, for investigating neurological disorders and for clinical diagnostic applications. Structural brain network (e.g. DTI) and functional brain network (e.g. fMRI) are the primary networks of interest. Most existing works in brain network analysis focus on either structural or functional connectivity, which cannot leverage the complementary information from each other. Although multi-view learning methods have been proposed to learn from both networks (or views), these methods aim to reach a consensus among multiple views, and thus distinct intrinsic properties of each view may be ignored. How to jointly learn representations from structural and functional brain networks while preserving their inherent properties is a critical problem. In this paper, we propose a framework of Siamese community-preserving graph convolutional network (SCP-GCN) to learn the structural and functional joint embedding of brain networks. Specifically, we use graph convolutions to learn the structural and functional joint embedding, where the graph structure is defined with structural connectivity and node features are from the functional connectivity. Moreover, we propose to preserve the community structure of brain networks in the graph convolutions by considering the intra-community and inter-community properties in the learning process. Furthermore, we use Siamese architecture which models the pair-wise similarity learning to guide the learning process. To evaluate the proposed approach, we conduct extensive experiments on two real brain network datasets. The experimental results demonstrate the superior performance of the proposed approach in structural and functional joint embedding for neurological disorder analysis, indicating its promising value for clinical applications.
Flow prediction (e.g., crowd flow, traffic flow) with features of spatial-temporal is increasingly investigated in AI research field. It is very challenging due to the complicated spatial dependencies between different locations and dynamic temporal dependencies among different time intervals. Although measurements of both dependencies are employed, existing methods suffer from the following two problems. First, the temporal dependencies are measured either uniformly or bias against long-term dependencies, which overlooks the distinctive impacts of short-term and long-term temporal dependencies. Second, the existing methods capture spatial and temporal dependencies independently, which wrongly assumes that the correlations between these dependencies are weak and ignores the complicated mutual influences between them. To address these issues, we propose a Spatial-Temporal Self-Attention Network (ST-SAN). As the path-length of attending long-term dependency is shorter in the self-attention mechanism, the vanishing of long-term temporal dependencies is prevented. In addition, since our model relies solely on attention mechanisms, the spatial and temporal dependencies can be simultaneously measured. Experimental results on real-world data demonstrate that, in comparison with state-of-the-art methods, our model reduces the root mean square errors by 9% in inflow prediction and 4% in outflow prediction on Taxi-NYC data, which is very significant compared to the previous improvement.
Advanced methods of applying deep learning to structured data such as graphs have been proposed in recent years. In particular, studies have focused on generalizing convolutional neural networks to graph data, which includes redefining the convolution and the downsampling (pooling) operations for graphs. The method of generalizing the convolution operation to graphs has been proven to improve performance and is widely used. However, the method of applying downsampling to graphs is still difficult to perform and has room for improvement. In this paper, we propose a graph pooling method based on self-attention. Self-attention using graph convolution allows our pooling method to consider both node features and graph topology. To ensure a fair comparison, the same training procedures and model architectures were used for the existing pooling methods and our method. The experimental results demonstrate that our method achieves superior graph classification performance on the benchmark datasets using a reasonable number of parameters.
Worldwide, several cases go undiagnosed due to poor healthcare support in remote areas. In this context, a centralized system is needed for effective monitoring and analysis of the medical records. A web-based patient diagnostic system is a central platform to store the medical history and predict the possible disease based on the current symptoms experienced by a patient to ensure faster and accurate diagnosis. Early disease prediction can help the users determine the severity of the disease and take quick action. The proposed web-based disease prediction system utilizes machine learning based classification techniques on a data set acquired from the National Centre of Disease Control (NCDC). $K$-nearest neighbor (K-NN), random forest and naive bayes classification approaches are utilized and an ensemble voting algorithm is also proposed where each classifier is assigned weights dynamically based on the prediction confidence. The proposed system is also equipped with a recommendation scheme to recommend the type of tests based on the existing symptoms of the patient, so that necessary precautions can be taken. A centralized database ensures that the medical data is preserved and there is transparency in the system. The tampering into the system is prevented by giving the no updation rights once the diagnosis is created.
Ride-hailing demand prediction is an essential task in spatial-temporal data mining. Accurate Ride-hailing demand prediction can help to pre-allocate resources, improve vehicle utilization and user experiences. Graph Convolutional Networks (GCN) is commonly used to model the complicated irregular non-Euclidean spatial correlations. However, existing GCN-based ride-hailing demand prediction methods only assign the same importance to different neighbor regions, and maintain a fixed graph structure with static spatial relationships throughout the timeline when extracting the irregular non-Euclidean spatial correlations. In this paper, we propose the Spatial-Temporal Dynamic Graph Attention Network (STDGAT), a novel ride-hailing demand prediction method. Based on the attention mechanism of GAT, STDGAT extracts different pair-wise correlations to achieve the adaptive importance allocation for different neighbor regions. Moreover, in STDGAT, we design a novel time-specific commuting-based graph attention mode to construct a dynamic graph structure for capturing the dynamic time-specific spatial relationships throughout the timeline. Extensive experiments are conducted on a real-world ride-hailing demand dataset, and the experimental results demonstrate the significant improvement of our method on three evaluation metrics RMSE, MAPE and MAE over state-of-the-art baselines.
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