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Register a new userDiffeomorphic density matching by optimal information transport
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We address the following problem: given two smooth densities on a manifold, find an optimal diffeomorphism that transforms one density into the other. Our framework builds on connections between the Fisher-Rao information metric on the space of probability densities and right-invariant metrics on the infinite-dimensional manifold of diffeomorphisms. This optimal information transport, and modifications thereof, allows us to construct numerical algorithms for density matching. The algorithms are inherently more efficient than those based on optimal mass transport or diffeomorphic registration. Our methods have applications in medical image registration, texture mapping, image morphing, non-uniform random sampling, and mesh adaptivity. Some of these applications are illustrated in examples.
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In this article we explore an algorithm for diffeomorphic random sampling of nonuniform probability distributions on Riemannian manifolds. The algorithm is based on optimal information transport (OIT)---an analogue of optimal mass transport (OMT). Our framework uses the deep geometric connections between the Fisher-Rao metric on the space of probability densities and the right-invariant information metric on the group of diffeomorphisms. The resulting sampling algorithm is a promising alternative to OMT, in particular as our formulation is semi-explicit, free of the nonlinear Monge--Ampere equation. Compared to Markov Chain Monte Carlo methods, we expect our algorithm to stand up well when a large number of samples from a low dimensional nonuniform distribution is needed.
In this book chapter we study the Riemannian Geometry of the density registration problem: Given two densities (not necessarily probability densities) defined on a smooth finite dimensional manifold find a diffeomorphism which transforms one to the other. This problem is motivated by the medical imaging application of tracking organ motion due to respiration in Thoracic CT imaging where the fundamental physical property of conservation of mass naturally leads to modeling CT attenuation as a density. We will study the intimate link between the Riemannian metrics on the space of diffeomorphisms and those on the space of densities. We finally develop novel computationally efficient algorithms and demonstrate there applicability for registering RCCT thoracic imaging.
We develop an operator splitting approach to solve diffeomorphic matching problems for sequences of surfaces in three-dimensional space. The goal is to smoothly match, at a very fast rate, finite sequences of observed 3D-snapshots extracted from movies recording the smooth dynamic deformations of soft surfaces. We have implemented our algorithms in a proprietary software installed at The Methodist Hospital (Cardiology) to monitor mitral valve strain through computer analysis of noninvasive patients echocardiographies.
We propose a variational model with diffeomorphic optimal transportation for joint image reconstruction and motion estimation. The proposed model is a production of assembling the Wasserstein distance with the Benamou--Brenier formula in optimal transportation and the flow of diffeomorphisms involved in large deformation diffeomorphic metric mapping, which is suitable for the scenario of spatiotemporal imaging with large diffeomorphic and mass-preserving deformations. Specifically, we first use the Benamou--Brenier formula to characterize the optimal transport cost among the flow of mass-preserving images, and restrict the velocity field into the admissible Hilbert space to guarantee the generated deformation flow being diffeomorphic. We then gain the ODE-constrained equivalent formulation for Benamou--Brenier formula. We finally obtain the proposed model with ODE constraint following the framework that presented in our previous work. We further get the equivalent PDE-constrained optimal control formulation. The proposed model is compared against several existing alternatives theoretically. The alternating minimization algorithm is presented for solving the time-discretized version of the proposed model with ODE constraint. Several important issues on the proposed model and associated algorithms are also discussed. Particularly, we present several potential models based on the proposed diffeomorphic optimal transportation. Under appropriate conditions, the proposed algorithm also provides a new scheme to solve the models using quadratic Wasserstein distance. The performance is finally evaluated by several numerical experiments in space-time tomography, where the data is measured from the concerned sequential images with sparse views and/or various noise levels.
In this article we study the problem of thoracic image registration, in particular the estimation of complex anatomical deformations associated with the breathing cycle. Using the intimate link between the Riemannian geometry of the space of diffeomorphisms and the space of densities, we develop an image registration framework that incorporates both the fundamental law of conservation of mass as well as spatially varying tissue compressibility properties. By exploiting the geometrical structure, the resulting algorithm is computationally efficient, yet widely general.
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