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Comparative Study Between the Results of Treatment of Urethral Stricture by Laser and Cold Knife Urethrotomy

مقارنة النتائج العلاجية لخزع تضيق الإحليل بالليزر مع الخزع البارد

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 Publication date 2013
and research's language is العربية
 Created by Shamra Editor




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Our study included 40 patients with a single length of less than 1 cm Urethral Stricture, between the ages of (20-75) years, reviewed the Assad University Hospital (Urinary clinic and Emergency Room) in Latakia between 2011 - 2012. Patients were distributed in two groups (A)-(B). The first group were treated using the technique of laser helium. The second group treated using a cold knife (a traditional biopsy). Patients were distributed in both groups without any considerations or statistical differences in the Pathogenicity mechanism, the stricture site, or any clinical diseases caused by them, but that all patients have a a single Urethral Stricture that does not exceed a length of 1 cm. The effectiveness of treatment were then evaluate using Uroflowmetry, where all patients was conducted to measure the rate of flow of urine before treatment and after treatment at 3 months and then after 6 months. Statistical study showed clear differences in the efficiency of treatment in favor of laser Urethrotomy(0,05> P). As we compare our results with three global studies and pointed to the compatibility with sites.


Artificial intelligence review:
Research summary
تتناول هذه الدراسة المقارنة بين نتائج علاج تضيق الإحليل باستخدام تقنية الليزر الهولميوم والخزع بالسكين البارد. شملت الدراسة 40 مريضًا تتراوح أعمارهم بين 20 و75 عامًا، تم تقسيمهم إلى مجموعتين: الأولى عولجت بالليزر الهولميوم، والثانية بالخزع التقليدي. تم تقييم فعالية العلاج باستخدام قياس معدل جريان البول قبل العلاج وبعده بـ 3 و6 أشهر. أظهرت النتائج فروقًا واضحة لصالح الخزع بالليزر في تحسين معدل جريان البول. كما تم مقارنة النتائج مع دراسات عالمية أخرى، وأشارت النتائج إلى توافق كبير مع بعض الدراسات واختلافات مع أخرى. توصي الدراسة بضرورة المتابعة الدورية للمرضى واستخدام أحدث التقنيات في العلاج.
Critical review
دراسة نقدية: تعتبر هذه الدراسة خطوة مهمة في مجال علاج تضيق الإحليل، حيث تقدم مقارنة واضحة بين تقنيتين مختلفتين. ومع ذلك، يمكن الإشارة إلى بعض النقاط التي قد تحتاج إلى تحسين. أولاً، حجم العينة صغير نسبيًا مما قد يؤثر على تعميم النتائج. ثانيًا، لم يتم توضيح تفاصيل كافية حول العوامل المؤثرة الأخرى مثل الحالة الصحية العامة للمرضى والتي قد تؤثر على النتائج. ثالثًا، يفضل إجراء دراسات متابعة لفترة أطول من 6 أشهر لتقييم النتائج على المدى البعيد. وأخيرًا، يمكن أن تكون هناك حاجة لمزيد من الدراسات التي تشمل تقنيات علاجية أخرى للمقارنة.
Questions related to the research
  1. ما هي الفئة العمرية للمرضى المشاركين في الدراسة؟

    تراوحت أعمار المرضى المشاركين في الدراسة بين 20 و75 عامًا.

  2. ما هي التقنية التي أظهرت فعالية أكبر في علاج تضيق الإحليل؟

    أظهرت تقنية الليزر الهولميوم فعالية أكبر في علاج تضيق الإحليل مقارنة بالخزع بالسكين البارد.

  3. ما هو المعيار المستخدم لتقييم فعالية العلاج في الدراسة؟

    تم تقييم فعالية العلاج باستخدام قياس معدل جريان البول (Uroflowmetry) قبل العلاج وبعده بـ 3 و6 أشهر.

  4. هل تم مقارنة نتائج الدراسة مع دراسات عالمية أخرى؟

    نعم، تم مقارنة نتائج الدراسة مع ثلاث دراسات عالمية أخرى وأشارت النتائج إلى توافق كبير مع بعضها واختلافات مع أخرى.


References used
Wein , A. J. Kavoussi, L. R. Novick, A. C. Partin, A.W. Peters, C.A. Campbell- Walsh Urology. 9th ed, Saunders Elsevier, Philadelphia USA, 2007, 3945
Cookson M. S.; Graham  S. D.; GLENN J. F. Glenn's Urologic Surgery. 5th ed Lippincott Williams & Wilkins New York & London & Tokyo 2005. 2443
KONETY, B. R. WILLIAMS, R. D. Smith's General Urology. 18th Ed, Humana Press, NY USA, 2006, 654
Sachse H (1974) Zur behandlung der Harnrohrenstriktur;Die transurethrale Schlitzung unter Sicht mit scharfenSchnitt. Fortschr Med 92:12–15
Giannakopoulos X, Grammeniatis E, Gratzios A et al (1997Sachseurethrotomy versus endoscopic urethrotomy plus transurethral resection of the fibrous callus (Guillemin’stechnique) in the treatment of urethral stricture. Urology49:243–247
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