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Register a new userSemi-Supervised Variational Reasoning for Medical Dialogue Generation
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Dongdong Li
Publication date
2021
fields
Informatics Engineering
and research's language is
English
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Medical dialogue generation aims to provide automatic and accurate responses to assist physicians to obtain diagnosis and treatment suggestions in an efficient manner. In medical dialogues two key characteristics are relevant for response generation: patient states (such as symptoms, medication) and physician actions (such as diagnosis, treatments). In medical scenarios large-scale human annotations are usually not available, due to the high costs and privacy requirements. Hence, current approaches to medical dialogue generation typically do not explicitly account for patient states and physician actions, and focus on implicit representation instead. We propose an end-to-end variational reasoning approach to medical dialogue generation. To be able to deal with a limited amount of labeled data, we introduce both patient state and physician action as latent variables with categorical priors for explicit patient state tracking and physician policy learning, respectively. We propose a variational Bayesian generative approach to approximate posterior distributions over patient states and physician actions. We use an efficient stochastic gradient variational Bayes estimator to optimize the derived evidence lower bound, where a 2-stage collapsed inference method is proposed to reduce the bias during model training. A physician policy network composed of an action-classifier and two reasoning detectors is proposed for augmented reasoning ability. We conduct experiments on three datasets collected from medical platforms. Our experimental results show that the proposed method outperforms state-of-the-art baselines in terms of objective and subjective evaluation metrics. Our experiments also indicate that our proposed semi-supervised reasoning method achieves a comparable performance as state-of-the-art fully supervised learning baselines for physician policy learning.
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Human doctors with well-structured medical knowledge can diagnose a disease merely via a few conversations with patients about symptoms. In contrast, existing knowledge-grounded dialogue systems often require a large number of dialogue instances to learn as they fail to capture the correlations between different diseases and neglect the diagnostic experience shared among them. To address this issue, we propose a more natural and practical paradigm, i.e., low-resource medical dialogue generation, which can transfer the diagnostic experience from source diseases to target ones with a handful of data for adaptation. It is capitalized on a commonsense knowledge graph to characterize the prior disease-symptom relations. Besides, we develop a Graph-Evolving Meta-Learning (GEML) framework that learns to evolve the commonsense graph for reasoning disease-symptom correlations in a new disease, which effectively alleviates the needs of a large number of dialogues. More importantly, by dynamically evolving disease-symptom graphs, GEML also well addresses the real-world challenges that the disease-symptom correlations of each disease may vary or evolve along with more diagnostic cases. Extensive experiment results on the CMDD dataset and our newly-collected Chunyu dataset testify the superiority of our approach over state-of-the-art approaches. Besides, our GEML can generate an enriched dialogue-sensitive knowledge graph in an online manner, which could benefit other tasks grounded on knowledge graph.
Cross-domain natural language generation (NLG) is still a difficult task within spoken dialogue modelling. Given a semantic representation provided by the dialogue manager, the language generator should generate sentences that convey desired information. Traditional template-based generators can produce sentences with all necessary information, but these sentences are not sufficiently diverse. With RNN-based models, the diversity of the generated sentences can be high, however, in the process some information is lost. In this work, we improve an RNN-based generator by considering latent information at the sentence level during generation using the conditional variational autoencoder architecture. We demonstrate that our model outperforms the original RNN-based generator, while yielding highly diverse sentences. In addition, our model performs better when the training data is limited.
Text-based Question Generation (QG) aims at generating natural and relevant questions that can be answered by a given answer in some context. Existing QG models suffer from a semantic drift problem, i.e., the semantics of the model-generated question drifts away from the given context and answer. In this paper, we first propose two semantics-enhanced rewards obtained from downstream question paraphrasing and question answering tasks to regularize the QG model to generate semantically valid questions. Second, since the traditional evaluation metrics (e.g., BLEU) often fall short in evaluating the quality of generated questions, we propose a QA-based evaluation method which measures the QG models ability to mimic human annotators in generating QA training data. Experiments show that our method achieves the new state-of-the-art performance w.r.t. traditional metrics, and also performs best on our QA-based evaluation metrics. Further, we investigate how to use our QG model to augment QA datasets and enable semi-supervised QA. We propose two ways to generate synthetic QA pairs: generate new questions from existing articles or collect QA pairs from new articles. We also propose two empirically effective strategies, a data filter and mixing mini-batch training, to properly use the QG-generated data for QA. Experiments show that our method improves over both BiDAF and BERT QA baselines, even without introducing new articles.
Commonsense inference to understand and explain human language is a fundamental research problem in natural language processing. Explaining human conversations poses a great challenge as it requires contextual understanding, planning, inference, and several aspects of reasoning including causal, temporal, and commonsense reasoning. In this work, we introduce CIDER -- a manually curated dataset that contains dyadic dialogue explanations in the form of implicit and explicit knowledge triplets inferred using contextual commonsense inference. Extracting such rich explanations from conversations can be conducive to improving several downstream applications. The annotated triplets are categorized by the type of commonsense knowledge present (e.g., causal, conditional, temporal). We set up three different tasks conditioned on the annotated dataset: Dialogue-level Natural Language Inference, Span Extraction, and Multi-choice Span Selection. Baseline results obtained with transformer-based models reveal that the tasks are difficult, paving the way for promising future research. The dataset and the baseline implementations are publicly available at https://cider-task.github.io/cider/.
Developing conversational agents to interact with patients and provide primary clinical advice has attracted increasing attention due to its huge application potential, especially in the time of COVID-19 Pandemic. However, the training of end-to-end neural-based medical dialogue system is restricted by an insufficient quantity of medical dialogue corpus. In this work, we make the first attempt to build and release a large-scale high-quality Medical Dialogue dataset related to 12 types of common Gastrointestinal diseases named MedDG, with more than 17K conversations collected from the online health consultation community. Five different categories of entities, including diseases, symptoms, attributes, tests, and medicines, are annotated in each conversation of MedDG as additional labels. To push forward the future research on building expert-sensitive medical dialogue system, we proposes two kinds of medical dialogue tasks based on MedDG dataset. One is the next entity prediction and the other is the doctor response generation. To acquire a clear comprehension on these two medical dialogue tasks, we implement several state-of-the-art benchmarks, as well as design two dialogue models with a further consideration on the predicted entities. Experimental results show that the pre-train language models and other baselines struggle on both tasks with poor performance in our dataset, and the response quality can be enhanced with the help of auxiliary entity information. From human evaluation, the simple retrieval model outperforms several state-of-the-art generative models, indicating that there still remains a large room for improvement on generating medically meaningful responses.
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