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Spatiotemporal impacts of human activities and socio-demographics during the COVID-19 outbreak in the U.S

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 Added by Lu Ling
 Publication date 2021
  fields Physics Biology
and research's language is English




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Understanding influencing factors is essential for the surveillance and prevention of infectious diseases, and the factors are likely to vary spatially and temporally as the disease progresses. Taking daily cases and deaths data during the coronavirus disease 2019 (COVID-19) outbreak in the U.S. as a case study, we develop a mobility-augmented geographically and temporally weighted regression (M-GTWR) model to quantify the spatiotemporal impacts of social-demographic factors and human activities on the COVID-19 dynamics. Different from the base GTWR model, we incorporate a mobility-adjusted distance weight matrix where travel mobility is used in addition to the spatial adjacency to capture the correlations among local observations. The model residuals suggest that the proposed model achieves a substantial improvement over other benchmark methods in addressing the spatiotemporal nonstationarity. Our results reveal that the impacts of social-demographic and human activity variables present significant spatiotemporal heterogeneity. In particular, a 1% increase in population density may lead to 0.63% and 0.71% more daily cases and deaths, and a 1% increase in the mean commuting time may result in 0.22% and 0.95% increases in daily cases and deaths. Although increased human activities will, in general, intensify the disease outbreak, we report that the effects of grocery and pharmacy-related activities are insignificant in areas with high population density. And activities at the workplace and public transit are found to either increase or decrease the number of cases and deaths, depending on particular locations. The results of our study establish a quantitative framework for identifying influencing factors during a disease outbreak, and the obtained insights may have significant implications in guiding the policy-making against infectious diseases.



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In March of this year, COVID-19 was declared a pandemic and it continues to threaten public health. This global health crisis imposes limitations on daily movements, which have deteriorated every sector in our society. Understanding public reactions to the virus and the non-pharmaceutical interventions should be of great help to fight COVID-19 in a strategic way. We aim to provide tangible evidence of the human mobility trends by comparing the day-by-day variations across the U.S. Large-scale public mobility at an aggregated level is observed by leveraging mobile device location data and the measures related to social distancing. Our study captures spatial and temporal heterogeneity as well as the sociodemographic variations regarding the pandemic propagation and the non-pharmaceutical interventions. All mobility metrics adapted capture decreased public movements after the national emergency declaration. The population staying home has increased in all states and becomes more stable after the stay-at-home order with a smaller range of fluctuation. There exists overall mobility heterogeneity between the income or population density groups. The public had been taking active responses, voluntarily staying home more, to the in-state confirmed cases while the stay-at-home orders stabilize the variations. The study suggests that the public mobility trends conform with the government message urging to stay home. We anticipate our data-driven analysis offers integrated perspectives and serves as evidence to raise public awareness and, consequently, reinforce the importance of social distancing while assisting policymakers.
The sudden outbreak of the Coronavirus disease (COVID-19) swept across the world in early 2020, triggering the lockdowns of several billion people across many countries, including China, Spain, India, the U.K., Italy, France, Germany, and most states of the U.S. The transmission of the virus accelerated rapidly with the most confirmed cases in the U.S., and New York City became an epicenter of the pandemic by the end of March. In response to this national and global emergency, the NSF Spatiotemporal Innovation Center brought together a taskforce of international researchers and assembled implemented strategies to rapidly respond to this crisis, for supporting research, saving lives, and protecting the health of global citizens. This perspective paper presents our collective view on the global health emergency and our effort in collecting, analyzing, and sharing relevant data on global policy and government responses, geospatial indicators of the outbreak and evolving forecasts; in developing research capabilities and mitigation measures with global scientists, promoting collaborative research on outbreak dynamics, and reflecting on the dynamic responses from human societies.
Non-pharmacologic interventions (NPIs) are one method to mitigate the spread and effects of the COVID-19 pandemic in the United States. NPIs promote protective actions to reduce exposure risk and can reduce mobility patterns within communities. Growing research literature suggests that socially vulnerable populations are disproportionately impacted with higher infection and higher fatality rates of COVID-19, though there is limited understanding of the underlying mechanisms to this health disparity. Thus, the research examines two distinct and complimentary datasets at a granular scale for five urban locations. Through statistical and spatial analyses, the research extensively investigates the exposure risk reduction of socially vulnerable populations due to NPIs. The mobility dataset tracks population movement across ZIP codes; it is used for an origin-destination network analysis. The population activity dataset is based on the number of visits from census block groups (CBG) to points of interest (POIs), such as grocery stores, restaurants, education centers, and medical facilities; it is used for network analysis of population-facilities interactions. The mobility dataset showed that, after the implementation of NPIs, socially vulnerable populations engaged in increased mobility in the form of inflow between ZIP code areas. Similarly, population activity analysis showed an increased exposure risk for socially vulnerable populations based on a greater number of inflow visits of CBGs to POIs, which increases the risk of contact at POIs, and a greater number of outflow visits from POIs to home CBGs, which increases risk of transmission within CBGs. These findings can assist emergency planners and public health officials in comprehending how different groups are able to implement protective actions and can inform more equitable and data-driven NPI policies for future epidemics.
143 - Xinyu Gao , Chao Fan , Yang Yang 2020
The spread of pandemics such as COVID-19 is strongly linked to human activities. The objective of this paper is to specify and examine early indicators of disease spread risk in cities during the initial stages of outbreak based on patterns of human activities obtained from digital trace data. In this study, the Venables distance (D_v), and the activity density (D_a) are used to quantify and evaluate human activities for 193 US counties, whose cumulative number of confirmed cases was greater than 100 as of March 31, 2020. Venables distance provides a measure of the agglomeration of the level of human activities based on the average distance of human activities across a city or a county (less distance could lead to a greater contact risk). Activity density provides a measure of level of overall activity level in a county or a city (more activity could lead to a greater risk). Accordingly, Pearson correlation analysis is used to examine the relationship between the two human activity indicators and the basic reproduction number in the following weeks. The results show statistically significant correlations between the indicators of human activities and the basic reproduction number in all counties, as well as a significant leader-follower relationship (time lag) between them. The results also show one to two weeks lag between the change in activity indicators and the decrease in the basic reproduction number. This result implies that the human activity indicators provide effective early indicators for the spread risk of the pandemic during the early stages of the outbreak. Hence, the results could be used by the authorities to proactively assess the risk of disease spread by monitoring the daily Venables distance and activity density in a proactive manner.
The current outbreak of the coronavirus disease 2019 (COVID-19) is an unprecedented example of how fast an infectious disease can spread around the globe (especially in urban areas) and the enormous impact it causes on public health and socio-economic activities. Despite the recent surge of investigations about different aspects of the COVID-19 pandemic, we still know little about the effects of city size on the propagation of this disease in urban areas. Here we investigate how the number of cases and deaths by COVID-19 scale with the population of Brazilian cities. Our results indicate small towns are proportionally more affected by COVID-19 during the initial spread of the disease, such that the cumulative numbers of cases and deaths per capita initially decrease with population size. However, during the long-term course of the pandemic, this urban advantage vanishes and large cities start to exhibit higher incidence of cases and deaths, such that every 1% rise in population is associated with a 0.14% increase in the number of fatalities per capita after about four months since the first two daily deaths. We argue that these patterns may be related to the existence of proportionally more health infrastructure in the largest cities and a lower proportion of older adults in large urban areas. We also find the initial growth rate of cases and deaths to be higher in large cities; however, these growth rates tend to decrease in large cities and to increase in small ones over time.
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