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Register a new userEarly Indicators of COVID-19 Spread Risk Using Digital Trace Data of Population Activities
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The spread of pandemics such as COVID-19 is strongly linked to human activities. The objective of this paper is to specify and examine early indicators of disease spread risk in cities during the initial stages of outbreak based on patterns of human activities obtained from digital trace data. In this study, the Venables distance (D_v), and the activity density (D_a) are used to quantify and evaluate human activities for 193 US counties, whose cumulative number of confirmed cases was greater than 100 as of March 31, 2020. Venables distance provides a measure of the agglomeration of the level of human activities based on the average distance of human activities across a city or a county (less distance could lead to a greater contact risk). Activity density provides a measure of level of overall activity level in a county or a city (more activity could lead to a greater risk). Accordingly, Pearson correlation analysis is used to examine the relationship between the two human activity indicators and the basic reproduction number in the following weeks. The results show statistically significant correlations between the indicators of human activities and the basic reproduction number in all counties, as well as a significant leader-follower relationship (time lag) between them. The results also show one to two weeks lag between the change in activity indicators and the decrease in the basic reproduction number. This result implies that the human activity indicators provide effective early indicators for the spread risk of the pandemic during the early stages of the outbreak. Hence, the results could be used by the authorities to proactively assess the risk of disease spread by monitoring the daily Venables distance and activity density in a proactive manner.
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The ongoing COVID-19 pandemic has created a global crisis of massive scale. Prior research indicates that human mobility is one of the key factors involved in viral spreading. Indeed, in a connected planet, rapid world-wide spread is enabled by long-distance air-, land- and sea-transportation among countries and continents, and subsequently fostered by commuting trips within densely populated cities. While early travel restrictions contribute to delayed disease spread, their utility is much reduced if the disease has a long incubation period or if there is asymptomatic transmission. Given the lack of vaccines, public health officials have mainly relied on non-pharmaceutical interventions, including social distancing measures, curfews, and stay-at-home orders. Here we study the impact of city organization on its susceptibility to disease spread, and amenability to interventions. Cities can be classified according to their mobility in a spectrum between compact-hierarchical and decentralized-sprawled. Our results show that even though hierarchical cities are more susceptible to the rapid spread of epidemics, their organization makes mobility restrictions quite effective. Conversely, sprawled cities are characterized by a much slower initial spread, but are less responsive to mobility restrictions. These findings hold globally across cities in diverse geographical locations and a broad range of sizes. Our empirical measurements are confirmed by a simulation of COVID-19 spread in urban areas through a compartmental model. These results suggest that investing resources on early monitoring and prompt ad-hoc interventions in more vulnerable cities may prove most helpful in containing and reducing the impact of present and future pandemics.
Non-pharmacologic interventions (NPIs) are one method to mitigate the spread and effects of the COVID-19 pandemic in the United States. NPIs promote protective actions to reduce exposure risk and can reduce mobility patterns within communities. Growing research literature suggests that socially vulnerable populations are disproportionately impacted with higher infection and higher fatality rates of COVID-19, though there is limited understanding of the underlying mechanisms to this health disparity. Thus, the research examines two distinct and complimentary datasets at a granular scale for five urban locations. Through statistical and spatial analyses, the research extensively investigates the exposure risk reduction of socially vulnerable populations due to NPIs. The mobility dataset tracks population movement across ZIP codes; it is used for an origin-destination network analysis. The population activity dataset is based on the number of visits from census block groups (CBG) to points of interest (POIs), such as grocery stores, restaurants, education centers, and medical facilities; it is used for network analysis of population-facilities interactions. The mobility dataset showed that, after the implementation of NPIs, socially vulnerable populations engaged in increased mobility in the form of inflow between ZIP code areas. Similarly, population activity analysis showed an increased exposure risk for socially vulnerable populations based on a greater number of inflow visits of CBGs to POIs, which increases the risk of contact at POIs, and a greater number of outflow visits from POIs to home CBGs, which increases risk of transmission within CBGs. These findings can assist emergency planners and public health officials in comprehending how different groups are able to implement protective actions and can inform more equitable and data-driven NPI policies for future epidemics.
The rapid spread of COVID-19 in the United States has imposed a major threat to public health, the real economy, and human well-being. With the absence of effective vaccines, the preventive actions of social distancing and travel reduction are recognized as essential non-pharmacologic approaches to control the spread of COVID-19. Prior studies demonstrated that human movement and mobility drove the spatiotemporal distribution of COVID-19 in China. Little is known, however, about the patterns and effects of co-location reduction on cross-county transmission risk of COVID-19. This study utilizes Facebook co-location data for all counties in the United States from March to early May 2020. The analysis examines the synchronicity and time lag between travel reduction and pandemic growth trajectory to evaluate the efficacy of social distancing in ceasing the population co-location probabilities, and subsequently the growth in weekly new cases. The results show that the mitigation effects of co-location reduction appear in the growth of weekly new cases with one week of delay. Furthermore, significant segregation is found among different county groups which are categorized based on numbers of cases. The results suggest that within-group co-location probabilities remain stable, and social distancing policies primarily resulted in reduced cross-group co-location probabilities (due to travel reduction from counties with large number of cases to counties with low numbers of cases). These findings could have important practical implications for local governments to inform their intervention measures for monitoring and reducing the spread of COVID-19, as well as for adoption in future pandemics. Public policy, economic forecasting, and epidemic modeling need to account for population co-location patterns in evaluating transmission risk of COVID-19 across counties.
Understanding influencing factors is essential for the surveillance and prevention of infectious diseases, and the factors are likely to vary spatially and temporally as the disease progresses. Taking daily cases and deaths data during the coronavirus disease 2019 (COVID-19) outbreak in the U.S. as a case study, we develop a mobility-augmented geographically and temporally weighted regression (M-GTWR) model to quantify the spatiotemporal impacts of social-demographic factors and human activities on the COVID-19 dynamics. Different from the base GTWR model, we incorporate a mobility-adjusted distance weight matrix where travel mobility is used in addition to the spatial adjacency to capture the correlations among local observations. The model residuals suggest that the proposed model achieves a substantial improvement over other benchmark methods in addressing the spatiotemporal nonstationarity. Our results reveal that the impacts of social-demographic and human activity variables present significant spatiotemporal heterogeneity. In particular, a 1% increase in population density may lead to 0.63% and 0.71% more daily cases and deaths, and a 1% increase in the mean commuting time may result in 0.22% and 0.95% increases in daily cases and deaths. Although increased human activities will, in general, intensify the disease outbreak, we report that the effects of grocery and pharmacy-related activities are insignificant in areas with high population density. And activities at the workplace and public transit are found to either increase or decrease the number of cases and deaths, depending on particular locations. The results of our study establish a quantitative framework for identifying influencing factors during a disease outbreak, and the obtained insights may have significant implications in guiding the policy-making against infectious diseases.
The new coronavirus known as COVID-19 is spread world-wide since December 2019. Without any vaccination or medicine, the means of controlling it are limited to quarantine and social distancing. Here we study the spatio-temporal propagation of the first wave of the COVID-19 virus in China and compare it to other global locations. We provide a comprehensive picture of the spatial propagation from Hubei to other provinces in China in terms of distance, population size, and human mobility and their scaling relations. Since strict quarantine has been usually applied between cities, more insight about the temporal evolution of the disease can be obtained by analyzing the epidemic within cities, especially the time evolution of the infection, death, and recovery rates which affected by policies. We study and compare the infection rate in different cities in China and provinces in Italy and find that the disease spread is characterized by a two-stages process. At early times, at order of few days, the infection rate is close to a constant probably due to the lack of means to detect infected individuals before infection symptoms are observed. Then at later times it decays approximately exponentially due to quarantines. The time evolution of the death and recovery rates also distinguish between these two stages and reflect the health system situation which could be overloaded.
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