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Register a new userHAD-Net: A Hierarchical Adversarial Knowledge Distillation Network for Improved Enhanced Tumour Segmentation Without Post-Contrast Images
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Segmentation of enhancing tumours or lesions from MRI is important for detecting new disease activity in many clinical contexts. However, accurate segmentation requires the inclusion of medical images (e.g., T1 post contrast MRI) acquired after injecting patients with a contrast agent (e.g., Gadolinium), a process no longer thought to be safe. Although a number of modality-agnostic segmentation networks have been developed over the past few years, they have been met with limited success in the context of enhancing pathology segmentation. In this work, we present HAD-Net, a novel offline adversarial knowledge distillation (KD) technique, whereby a pre-trained teacher segmentation network, with access to all MRI sequences, teaches a student network, via hierarchical adversarial training, to better overcome the large domain shift presented when crucial images are absent during inference. In particular, we apply HAD-Net to the challenging task of enhancing tumour segmentation when access to post-contrast imaging is not available. The proposed network is trained and tested on the BraTS 2019 brain tumour segmentation challenge dataset, where it achieves performance improvements in the ranges of 16% - 26% over (a) recent modality-agnostic segmentation methods (U-HeMIS, U-HVED), (b) KD-Net adapted to this problem, (c) the pre-trained student network and (d) a non-hierarchical version of the network (AD-Net), in terms of Dice scores for enhancing tumour (ET). The network also shows improvements in tumour core (TC) Dice scores. Finally, the network outperforms both the baseline student network and AD-Net in terms of uncertainty quantification for enhancing tumour segmentation based on the BraTs 2019 uncertainty challenge metrics. Our code is publicly available at: https://github.com/SaverioVad/HAD_Net
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The pandemic of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) also known as COVID-19 has been spreading worldwide, causing rampant loss of lives. Medical imaging such as computed tomography (CT), X-ray, etc., plays a significant role in diagnosing the patients by presenting the excellent details about the structure of the organs. However, for any radiologist analyzing such scans is a tedious and time-consuming task. The emerging deep learning technologies have displayed its strength in analyzing such scans to aid in the faster diagnosis of the diseases and viruses such as COVID-19. In the present article, an automated deep learning based model, COVID-19 hierarchical segmentation network (CHS-Net) is proposed that functions as a semantic hierarchical segmenter to identify the COVID-19 infected regions from lungs contour via CT medical imaging. The CHS-Net is developed with the two cascaded residual attention inception U-Net (RAIU-Net) models where first generates lungs contour maps and second generates COVID-19 infected regions. RAIU-Net comprises of a residual inception U-Net model with spectral spatial and depth attention network (SSD), consisting of contraction and expansion phases of depthwise separable convolutions and hybrid pooling (max and spectral pooling) to efficiently encode and decode the semantic and varying resolution information. The CHS-Net is trained with the segmentation loss function that is the weighted average of binary cross entropy loss and dice loss to penalize false negative and false positive predictions. The approach is compared with the recently proposed research works on the basis of standard metrics. With extensive trials, it is observed that the proposed approach outperformed the recently proposed approaches and effectively segments the COVID-19 infected regions in the lungs.
We propose an efficient neural network for RAW image denoising. Although neural network-based denoising has been extensively studied for image restoration, little attention has been given to efficient denoising for compute limited and power sensitive devices, such as smartphones and smartwatches. In this paper, we present a novel architecture and a suite of training techniques for high quality denoising in mobile devices. Our work is distinguished by three main contributions. (1) Feature-Align layer that modulates the activations of an encoder-decoder architecture with the input noisy images. The auto modulation layer enforces attention to spatially varying noise that tend to be washed away by successive application of convolutions and non-linearity. (2) A novel Feature Matching Loss that allows knowledge distillation from large denoising networks in the form of a perceptual content loss. (3) Empirical analysis of our efficient model trained to specialize on different noise subranges. This opens additional avenue for model size reduction by sacrificing memory for compute. Extensive experimental validation shows that our efficient model produces high quality denoising results that compete with state-of-the-art large networks, while using significantly fewer parameters and MACs. On the Darmstadt Noise Dataset benchmark, we achieve a PSNR of 48.28dB, while using 263 times fewer MACs, and 17.6 times fewer parameters than the state-of-the-art network, which achieves 49.12dB.
Capturing visual image with a hyperspectral camera has been successfully applied to many areas due to its narrow-band imaging technology. Hyperspectral reconstruction from RGB images denotes a reverse process of hyperspectral imaging by discovering an inverse response function. Current works mainly map RGB images directly to corresponding spectrum but do not consider context information explicitly. Moreover, the use of encoder-decoder pair in current algorithms leads to loss of information. To address these problems, we propose a 4-level Hierarchical Regression Network (HRNet) with PixelShuffle layer as inter-level interaction. Furthermore, we adopt a residual dense block to remove artifacts of real world RGB images and a residual global block to build attention mechanism for enlarging perceptive field. We evaluate proposed HRNet with other architectures and techniques by participating in NTIRE 2020 Challenge on Spectral Reconstruction from RGB Images. The HRNet is the winning method of track 2 - real world images and ranks 3rd on track 1 - clean images. Please visit the project web page https://github.com/zhaoyuzhi/Hierarchical-Regression-Network-for-Spectral-Reconstruction-from-RGB-Images to try our codes and pre-trained models.
Automated vascular segmentation on optical coherence tomography angiography (OCTA) is important for the quantitative analyses of retinal microvasculature in neuroretinal and systemic diseases. Despite recent improvements, artifacts continue to pose challenges in segmentation. Our study focused on removing the speckle noise artifact from OCTA images when performing segmentation. Speckle noise is common in OCTA and is particularly prominent over large non-perfusion areas. It may interfere with the proper assessment of retinal vasculature. In this study, we proposed a novel Supervision Vessel Segmentation network (SVS-net) to detect vessels of different sizes. The SVS-net includes a new attention-based module to describe vessel positions and facilitate the understanding of the network learning process. The model is efficient and explainable and could be utilized to reduce the need for manual labeling. Our SVS-net had better performance in accuracy, recall, F1 score, and Kappa score when compared to other well recognized models.
The Medico: Multimedia Task 2020 focuses on developing an efficient and accurate computer-aided diagnosis system for automatic segmentation [3]. We participate in task 1, Polyps segmentation task, which is to develop algorithms for segmenting polyps on a comprehensive dataset. In this task, we propose methods combining Residual module, Inception module, Adaptive Convolutional neural network with U-Net model, and PraNet for semantic segmentation of various types of polyps in endoscopic images. We select 5 runs with different architecture and parameters in our methods. Our methods show potential results in accuracy and efficiency through multiple experiments, and our team is in the Top 3 best results with a Jaccard index of 0.765.
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