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Being expensive and time-consuming to collect massive COVID-19 image samples to train deep classification models, transfer learning is a promising approach by transferring knowledge from the abundant typical pneumonia datasets for COVID-19 image classification. However, negative transfer may deteriorate the performance due to the feature distribution divergence between two datasets and task semantic difference in diagnosing pneumonia and COVID-19 that rely on different characteristics. It is even more challenging when the target dataset has no labels available, i.e., unsupervised task transfer learning. In this paper, we propose a novel Task Adaptation Network (TAN) to solve this unsupervised task transfer problem. In addition to learning transferable features via domain-adversarial training, we propose a novel task semantic adaptor that uses the learning-to-learn strategy to adapt the task semantics. Experiments on three public COVID-19 datasets demonstrate that our proposed method achieves superior performance. Especially on COVID-DA dataset, TAN significantly increases the recall and F1 score by 5.0% and 7.8% compared to recently strong baselines. Moreover, we show that TAN also achieves superior performance on several public domain adaptation benchmarks.
Recent works have proven that many relevant visual tasks are closely related one to another. Yet, this connection is seldom deployed in practice due to the lack of practical methodologies to transfer learned concepts across different training processes. In this work, we introduce a novel adaptation framework that can operate across both task and domains. Our framework learns to transfer knowledge across tasks in a fully supervised domain (e.g., synthetic data) and use this knowledge on a different domain where we have only partial supervision (e.g., real data). Our proposal is complementary to existing domain adaptation techniques and extends them to cross tasks scenarios providing additional performance gains. We prove the effectiveness of our framework across two challenging tasks (i.e., monocular depth estimation and semantic segmentation) and four different domains (Synthia, Carla, Kitti, and Cityscapes).
Deep learning based analysis of histopathology images shows promise in advancing the understanding of tumor progression, tumor micro-environment, and their underpinning biological processes. So far, these approaches have focused on extracting information associated with annotations. In this work, we ask how much information can be learned from the tissue architecture itself. We present an adversarial learning model to extract feature representations of cancer tissue, without the need for manual annotations. We show that these representations are able to identify a variety of morphological characteristics across three cancer types: Breast, colon, and lung. This is supported by 1) the separation of morphologic characteristics in the latent space; 2) the ability to classify tissue type with logistic regression using latent representations, with an AUC of 0.97 and 85% accuracy, comparable to supervised deep models; 3) the ability to predict the presence of tumor in Whole Slide Images (WSIs) using multiple instance learning (MIL), achieving an AUC of 0.98 and 94% accuracy. Our results show that our model captures distinct phenotypic characteristics of real tissue samples, paving the way for further understanding of tumor progression and tumor micro-environment, and ultimately refining histopathological classification for diagnosis and treatment. The code and pretrained models are available at: https://github.com/AdalbertoCq/Adversarial-learning-of-cancer-tissue-representations
Recent reports suggest that a generic supervised deep CNN model trained on a large-scale dataset reduces, but does not remove, dataset bias. Fine-tuning deep models in a new domain can require a significant amount of labeled data, which for many applications is simply not available. We propose a new CNN architecture to exploit unlabeled and sparsely labeled target domain data. Our approach simultaneously optimizes for domain invariance to facilitate domain transfer and uses a soft label distribution matching loss to transfer information between tasks. Our proposed adaptation method offers empirical performance which exceeds previously published results on two standard benchmark visual domain adaptation tasks, evaluated across supervised and semi-supervised adaptation settings.
Building automatic technical support system is an important yet challenge task. Conceptually, to answer a user question on a technical forum, a human expert has to first retrieve relevant documents, and then read them carefully to identify the answer snippet. Despite huge success the researchers have achieved in coping with general domain question answering (QA), much less attentions have been paid for investigating technical QA. Specifically, existing methods suffer from several unique challenges (i) the question and answer rarely overlaps substantially and (ii) very limited data size. In this paper, we propose a novel framework of deep transfer learning to effectively address technical QA across tasks and domains. To this end, we present an adjustable joint learning approach for document retrieval and reading comprehension tasks. Our experiments on the TechQA demonstrates superior performance compared with state-of-the-art methods.
We propose a novel approach to image segmentation based on combining implicit spline representations with deep convolutional neural networks. This is done by predicting the control points of a bivariate spline function whose zero-set represents the segmentation boundary. We adapt several existing neural network architectures and design novel loss functions that are tailored towards providing implicit spline curve approximations. The method is evaluated on a congenital heart disease computed tomography medical imaging dataset. Experiments are carried out by measuring performance in various standard metrics for different networks and loss functions. We determine that splines of bidegree $(1,1)$ with $128times128$ coefficient resolution performed optimally for $512times 512$ resolution CT images. For our best network, we achieve an average volumetric test Dice score of almost 92%, which reaches the state of the art for this congenital heart disease dataset.