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Reinforced Contact Tracing and Epidemic Intervention

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 Added by Tao Feng
 Publication date 2021
and research's language is English




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The recent outbreak of COVID-19 poses a serious threat to peoples lives. Epidemic control strategies have also caused damage to the economy by cutting off humans daily commute. In this paper, we develop an Individual-based Reinforcement Learning Epidemic Control Agent (IDRLECA) to search for smart epidemic control strategies that can simultaneously minimize infections and the cost of mobility intervention. IDRLECA first hires an infection probability model to calculate the current infection probability of each individual. Then, the infection probabilities together with individuals health status and movement information are fed to a novel GNN to estimate the spread of the virus through human contacts. The estimated risks are used to further support an RL agent to select individual-level epidemic-control actions. The training of IDRLECA is guided by a specially designed reward function considering both the cost of mobility intervention and the effectiveness of epidemic control. Moreover, we design a constraint for control-action selection that eases its difficulty and further improve exploring efficiency. Extensive experimental results demonstrate that IDRLECA can suppress infections at a very low level and retain more than 95% of human mobility.

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We introduce a Reed-Frost epidemic model with recursive contact tracing and asymptomatic transmission. This generalizes the branching-process model introduced by the authors in a previous work [arxiv:2004.07237] to finite populations and general contact networks. We simulate the model numerically for two representative examples, the complete graph and the square lattice. On both networks, we observe clear signatures of a contact-tracing phase transition from an epidemic phase to an immune phase as contact-network coverage is increased. We verify that away from the singular line of perfect tracing, the finite-size scaling of the contact-tracing phase transition on each network lies in the corresponding percolation universality class. Finally, we use the model to quantify the efficacy of recursive contact-tracing in regimes where epidemic spread is not contained.
Contact-tracing is an essential tool in order to mitigate the impact of pandemic such as the COVID-19. In order to achieve efficient and scalable contact-tracing in real time, digital devices can play an important role. While a lot of attention has been paid to analyzing the privacy and ethical risks of the associated mobile applications, so far much less research has been devoted to optimizing their performance and assessing their impact on the mitigation of the epidemic. We develop Bayesian inference methods to estimate the risk that an individual is infected. This inference is based on the list of his recent contacts and their own risk levels, as well as personal information such as results of tests or presence of syndromes. We propose to use probabilistic risk estimation in order to optimize testing and quarantining strategies for the control of an epidemic. Our results show that in some range of epidemic spreading (typically when the manual tracing of all contacts of infected people becomes practically impossible, but before the fraction of infected people reaches the scale where a lock-down becomes unavoidable), this inference of individuals at risk could be an efficient way to mitigate the epidemic. Our approaches translate into fully distributed algorithms that only require communication between individuals who have recently been in contact. Such communication may be encrypted and anonymized and thus compatible with privacy preserving standards. We conclude that probabilistic risk estimation is capable to enhance performance of digital contact tracing and should be considered in the currently developed mobile applications.
AI systems are increasingly applied to complex tasks that involve interaction with humans. During training, such systems are potentially dangerous, as they havent yet learned to avoid actions that could cause serious harm. How can an AI system explore and learn without making a single mistake that harms humans or otherwise causes serious damage? For model-free reinforcement learning, having a human in the loop and ready to intervene is currently the only way to prevent all catastrophes. We formalize human intervention for RL and show how to reduce the human labor required by training a supervised learner to imitate the humans intervention decisions. We evaluate this scheme on Atari games, with a Deep RL agent being overseen by a human for four hours. When the class of catastrophes is simple, we are able to prevent all catastrophes without affecting the agents learning (whereas an RL baseline fails due to catastrophic forgetting). However, this scheme is less successful when catastrophes are more complex: it reduces but does not eliminate catastrophes and the supervised learner fails on adversarial examples found by the agent. Extrapolating to more challenging environments, we show that our implementation would not scale (due to the infeasible amount of human labor required). We outline extensions of the scheme that are necessary if we are to train model-free agents without a single catastrophe.
Vaccination is an important measure available for preventing or reducing the spread of infectious diseases. In this paper, an epidemic model including susceptible, infected, and imperfectly vaccinated compartments is studied on Watts-Strogatz small-world, Barabasi-Albert scale-free, and random scale-free networks. The epidemic threshold and prevalence are analyzed. For small-world networks, the effective vaccination intervention is suggested and its influence on the threshold and prevalence is analyzed. For scale-free networks, the threshold is found to be strongly dependent both on the effective vaccination rate and on the connectivity distribution. Moreover, so long as vaccination is effective, it can linearly decrease the epidemic prevalence in small-world networks, whereas for scale-free networks it acts exponentially. These results can help in adopting pragmatic treatment upon diseases in structured populations.
144 - Moyu Zhang 2021
With the increasing demands of personalized learning, knowledge tracing has become important which traces students knowledge states based on their historical practices. Factor analysis methods mainly use two kinds of factors which are separately related to students and questions to model students knowledge states. These methods use the total number of attempts of students to model students learning progress and hardly highlight the impact of the most recent relevant practices. Besides, current factor analysis methods ignore rich information contained in questions. In this paper, we propose Multi-Factors Aware Dual-Attentional model (MF-DAKT) which enriches question representations and utilizes multiple factors to model students learning progress based on a dual-attentional mechanism. More specifically, we propose a novel student-related factor which records the most recent attempts on relevant concepts of students to highlight the impact of recent exercises. To enrich questions representations, we use a pre-training method to incorporate two kinds of question information including questions relation and difficulty level. We also add a regularization term about questions difficulty level to restrict pre-trained question representations to fine-tuning during the process of predicting students performance. Moreover, we apply a dual-attentional mechanism to differentiate contributions of factors and factor interactions to final prediction in different practice records. At last, we conduct experiments on several real-world datasets and results show that MF-DAKT can outperform existing knowledge tracing methods. We also conduct several studies to validate the effects of each component of MF-DAKT.

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