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Register a new userUnpaired Multi-modal Segmentation via Knowledge Distillation
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Multi-modal learning is typically performed with network architectures containing modality-specific layers and shared layers, utilizing co-registered images of different modalities. We propose a novel learning scheme for unpaired cross-modality image segmentation, with a highly compact architecture achieving superior segmentation accuracy. In our method, we heavily reuse network parameters, by sharing all convolutional kernels across CT and MRI, and only employ modality-specific internal normalization layers which compute respective statistics. To effectively train such a highly compact model, we introduce a novel loss term inspired by knowledge distillation, by explicitly constraining the KL-divergence of our derived prediction distributions between modalities. We have extensively validated our approach on two multi-class segmentation problems: i) cardiac structure segmentation, and ii) abdominal organ segmentation. Different network settings, i.e., 2D dilated network and 3D U-net, are utilized to investigate our methods general efficacy. Experimental results on both tasks demonstrate that our novel multi-modal learning scheme consistently outperforms single-modal training and previous multi-modal approaches.
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The joint use of multiple imaging modalities for medical image segmentation has been widely studied in recent years. The fusion of information from different modalities has demonstrated to improve the segmentation accuracy, with respect to mono-modal segmentations, in several applications. However, acquiring multiple modalities is usually not possible in a clinical setting due to a limited number of physicians and scanners, and to limit costs and scan time. Most of the time, only one modality is acquired. In this paper, we propose KD-Net, a framework to transfer knowledge from a trained multi-modal network (teacher) to a mono-modal one (student). The proposed method is an adaptation of the generalized distillation framework where the student network is trained on a subset (1 modality) of the teachers inputs (n modalities). We illustrate the effectiveness of the proposed framework in brain tumor segmentation with the BraTS 2018 dataset. Using different architectures, we show that the student network effectively learns from the teacher and always outperforms the baseline mono-modal network in terms of segmentation accuracy.
Knowledge distillation~(KD) is an effective learning paradigm for improving the performance of lightweight student networks by utilizing additional supervision knowledge distilled from teacher networks. Most pioneering studies either learn from only a single teacher in their distillation learning methods, neglecting the potential that a student can learn from multiple teachers simultaneously, or simply treat each teacher to be equally important, unable to reveal the different importance of teachers for specific examples. To bridge this gap, we propose a novel adaptive multi-teacher multi-level knowledge distillation learning framework~(AMTML-KD), which consists two novel insights: (i) associating each teacher with a latent representation to adaptively learn instance-level teacher importance weights which are leveraged for acquiring integrated soft-targets~(high-level knowledge) and (ii) enabling the intermediate-level hints~(intermediate-level knowledge) to be gathered from multiple teachers by the proposed multi-group hint strategy. As such, a student model can learn multi-level knowledge from multiple teachers through AMTML-KD. Extensive results on publicly available datasets demonstrate the proposed learning framework ensures student to achieve improved performance than strong competitors.
Multi-label image classification is a fundamental but challenging task towards general visual understanding. Existing methods found the region-level cues (e.g., features from RoIs) can facilitate multi-label classification. Nevertheless, such methods usually require laborious object-level annotations (i.e., object labels and bounding boxes) for effective learning of the object-level visual features. In this paper, we propose a novel and efficient deep framework to boost multi-label classification by distilling knowledge from weakly-supervised detection task without bounding box annotations. Specifically, given the image-level annotations, (1) we first develop a weakly-supervised detection (WSD) model, and then (2) construct an end-to-end multi-label image classification framework augmented by a knowledge distillation module that guides the classification model by the WSD model according to the class-level predictions for the whole image and the object-level visual features for object RoIs. The WSD model is the teacher model and the classification model is the student model. After this cross-task knowledge distillation, the performance of the classification model is significantly improved and the efficiency is maintained since the WSD model can be safely discarded in the test phase. Extensive experiments on two large-scale datasets (MS-COCO and NUS-WIDE) show that our framework achieves superior performances over the state-of-the-art methods on both performance and efficiency.
This paper addresses the problem of model compression via knowledge distillation. To this end, we propose a new knowledge distillation method based on transferring feature statistics, specifically the channel-wise mean and variance, from the teacher to the student. Our method goes beyond the standard way of enforcing the mean and variance of the student to be similar to those of the teacher through an $L_2$ loss, which we found it to be of limited effectiveness. Specifically, we propose a new loss based on adaptive instance normalization to effectively transfer the feature statistics. The main idea is to transfer the learned statistics back to the teacher via adaptive instance normalization (conditioned on the student) and let the teacher network evaluate via a loss whether the statistics learned by the student are reliably transferred. We show that our distillation method outperforms other state-of-the-art distillation methods over a large set of experimental settings including different (a) network architectures, (b) teacher-student capacities, (c) datasets, and (d) domains.
In medical applications, the same anatomical structures may be observed in multiple modalities despite the different image characteristics. Currently, most deep models for multimodal segmentation rely on paired registered images. However, multimodal paired registered images are difficult to obtain in many cases. Therefore, developing a model that can segment the target objects from different modalities with unpaired images is significant for many clinical applications. In this work, we propose a novel two-stream translation and segmentation unified attentional generative adversarial network (UAGAN), which can perform any-to-any image modality translation and segment the target objects simultaneously in the case where two or more modalities are available. The translation stream is used to capture modality-invariant features of the target anatomical structures. In addition, to focus on segmentation-related features, we add attentional blocks to extract valuable features from the translation stream. Experiments on three-modality brain tumor segmentation indicate that UAGAN outperforms the existing methods in most cases.
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