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While Multiple Instance (MI) data are point patterns -- sets or multi-sets of unordered points -- appropriate statistical point pattern models have not been used in MI learning. This article proposes a framework for model-based MI learning using point process theory. Likelihood functions for point pattern data derived from point process theory enable principled yet conceptually transparent extensions of learning tasks, such as classification, novelty detection and clustering, to point pattern data. Furthermore, tractable point pattern models as well as solutions for learning and decision making from point pattern data are developed.
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Label noise will degenerate the performance of deep learning algorithms because deep neural networks easily overfit label errors. Let X and Y denote the instance and clean label, respectively. When Y is a cause of X, according to which many datasets have been constructed, e.g., SVHN and CIFAR, the distributions of P(X) and P(Y|X) are entangled. This means that the unsupervised instances are helpful to learn the classifier and thus reduce the side effect of label noise. However, it remains elusive on how to exploit the causal information to handle the label noise problem. In this paper, by leveraging a structural causal model, we propose a novel generative approach for instance-dependent label-noise learning. In particular, we show that properly modeling the instances will contribute to the identifiability of the label noise transition matrix and thus lead to a better classifier. Empirically, our method outperforms all state-of-the-art methods on both synthetic and real-world label-noise datasets.
Red blood cells are highly deformable and present in various shapes. In blood cell disorders, only a subset of all cells is morphologically altered and relevant for the diagnosis. However, manually labeling of all cells is laborious, complicated and introduces inter-expert variability. We propose an attention based multiple instance learning method to classify blood samples of patients suffering from blood cell disorders. Cells are detected using an R-CNN architecture. With the features extracted for each cell, a multiple instance learning method classifies patient samples into one out of four blood cell disorders. The attention mechanism provides a measure of the contribution of each cell to the overall classification and significantly improves the networks classification accuracy as well as its interpretability for the medical expert.
The performance of modern machine learning methods highly depends on their hyperparameter configurations. One simple way of selecting a configuration is to use default settings, often proposed along with the publication and implementation of a new algorithm. Those default values are usually chosen in an ad-hoc manner to work good enough on a wide variety of datasets. To address this problem, different automatic hyperparameter configuration algorithms have been proposed, which select an optimal configuration per dataset. This principled approach usually improves performance but adds additional algorithmic complexity and computational costs to the training procedure. As an alternative to this, we propose learning a set of complementary default values from a large database of prior empirical results. Selecting an appropriate configuration on a new dataset then requires only a simple, efficient and embarrassingly parallel search over this set. We demonstrate the effectiveness and efficiency of the approach we propose in comparison to random search and Bayesian Optimization.
In this work, we consider a manufactory process which can be described by a multiple-instance logistic regression model. In order to compute the maximum likelihood estimation of the unknown coefficient, an expectation-maximization algorithm is proposed, and the proposed modeling approach can be extended to identify the important covariates by adding the coefficient penalty term into the likelihood function. In addition to essential technical details, we demonstrate the usefulness of the proposed method by simulations and real examples.
We propose a new formulation of Multiple-Instance Learning (MIL), in which a unit of data consists of a set of instances called a bag. The goal is to find a good classifier of bags based on the similarity with a shapelet (or pattern), where the similarity of a bag with a shapelet is the maximum similarity of instances in the bag. In previous work, some of the training instances are chosen as shapelets with no theoretical justification. In our formulation, we use all possible, and thus infinitely many shapelets, resulting in a richer class of classifiers. We show that the formulation is tractable, that is, it can be reduced through Linear Programming Boosting (LPBoost) to Difference of Convex (DC) programs of finite (actually polynomial) size. Our theoretical result also gives justification to the heuristics of some of the previous work. The time complexity of the proposed algorithm highly depends on the size of the set of all instances in the training sample. To apply to the data containing a large number of instances, we also propose a heuristic option of the algorithm without the loss of the theoretical guarantee. Our empirical study demonstrates that our algorithm uniformly works for Shapelet Learning tasks on time-series classification and various MIL tasks with comparable accuracy to the existing methods. Moreover, we show that the proposed heuristics allow us to achieve the result with reasonable computational time.
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