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Register a new userMedipix3 Demonstration and understanding of near ideal detector performance for 60 & 80 keV electrons
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In our article we report first quantitative measurements of imaging performance for the current generation of hybrid pixel detector, Medipix3, as direct electron detector. Utilising beam energies of 60 & 80 keV, measurements of modulation transfer function (MTF) and detective quantum efficiency (DQE) have revealed that, in single pixel mode (SPM), energy threshold values can be chosen to maximize either the MTF or DQE, obtaining values near to, or even exceeding, those for an ideal detector. We have demonstrated that the Medipix3 charge summing mode (CSM) can deliver simultaneous, near ideal values of both MTF and DQE. To understand direct detection performance further we have characterized the detector response to single electron events, building an empirical model which can predict detector MTF and DQE performance based on energy threshold. Exemplifying our findings we demonstrate the Medipix3 imaging performance, recording a fully exposed electron diffraction pattern at 24-bit depth and images in SPM and CSM modes. Taken together our findings highlight that for transmission electron microscopy performed at low energies (energies <100 keV) thick hybrid pixel detectors provide an advantageous and alternative architecture for direct electron imaging
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Charged particle therapy (CPT) is an advanced modality of radiation therapy which has grown rapidly worldwide, driven by recent developments in technology and methods of delivery. To ensure safe and high quality treatments, various instruments are used for a range of different measurements such as for quality assurance, monitoring and dosimetry purposes. With the emergence of new and enhanced delivery techniques, systems with improved capabilities are needed to exceed existing performance limitations of conventional tools. The Medipix3 is a hybrid pixel detector able to count individual protons with millisecond time resolution at clinical flux with near instant readout and count rate linearity. The system has previously demonstrated use in medical and other applications, showing wide versatility and potential for particle therapy. In this work we present measurements of the Medipix3 detector in the 60 MeV ocular proton therapy beamline at the Clatterbridge Cancer Centre, UK. The beam current and lateral beam profiles were evaluated at multiple positions in the treatment line and compared with EBT3 Gafchromic film. The recorded count rate linearity and temporal analysis of the beam structure was measured with Medipix3 across the full range of available beam intensities, up to $3.12 times 10^{10}$ protons/s. We explore the capacity of Medipix3 to provide non-reference measurements and its applicability as a tool for dosimetry and beam monitoring for CPT. This is the first known time the performance of the Medipix3 detector technology has been tested within a clinical, high proton flux environment.
A high-intensity pulsed muon beam is becoming available at the at the Japan Proton Accelerator Research Complex (J-PARC). Many experiments to study fundamental physics using this high-intensity muon beam are proposed. An experiment to measure the muon magnetic moment anomaly ($g-2$) and the muon electric dipole moment (EDM) is one of these experiments and it requires a tracking detector for positrons from muon decay. Fine segmentation is required in a detector to tolerate the high rate of positrons. The time resolution is required to be much better than the muon anomalous spin precession period while a buffer depth of a front-end electronics needs to be much longer than the accelerated muon lifetime. Requirements of this detector also meet requirements of a measurement of the muonium hyperfine structure interval at the J-PARC and another experiment to measure the proton charge radius at Tohoku University. We have developed a single-sided silicon strip sensor with a 190 $mu$m pitch, a front-end electronics with a sampling rate of 200 MHz and a buffer memory depth of 8192, and a data acquisition system based on DAQ-Middleware for the J-PARC muon $g-2$/EDM experiment. We have fabricated detector modules consisting of this sensor and the front-end electronics. Performance of fabricated detector modules was evaluated at a laboratory and a beam test using the positron beam at Tohoku University. The detector is confirmed to satisfy all requirements of the experiments except for the time walk, which will be solved by the next version of a front-end electronics.
Scintillation light is used in liquid argon (LAr) neutrino detectors to provide a trigger signal, veto information against cosmic rays, and absolute event timing. In this work, we discuss additional opportunities offered by detectors with enhanced sensitivity to scintillation light, that is with light collection efficiencies of about $10^{-3}$. We focus on two key detector performance indicators for neutrino oscillation physics: calorimetric neutrino energy reconstruction and neutrino/antineutrino separation in a non-magnetized detector. Our results are based on detailed simulations, with neutrino interactions modelled according to the GENIE event generator, while the charge and light responses of a large LAr ideal detector are described by the Geant4 and NEST simulation tools. A neutrino energy resolution as good as 3.3% RMS for 4 GeV electron neutrino charged-current interactions can in principle be obtained in a large detector of this type, by using both charge and light information. By exploiting muon capture in argon and scintillation light information to veto muon decay electrons, we also obtain muon neutrino identification efficiencies of about 50%, and muon antineutrino misidentification rates at the few percent level, for few-GeV neutrino interactions that are fully contained. We argue that the construction of large LAr detectors with sufficiently high light collection efficiencies is in principle possible.
Detector developments are currently enabling new capabilities in the field of transmission electron microscopy (TEM). We have investigated the limits of a hybrid pixel detector, Medipix3, to record dynamic, time varying, electron signals. Operating with an energy of 60keV, we have utilised electrostatic deflection to oscillate electron beam position on the detector. Adopting a pump-probe imaging strategy we have demonstrated that temporal resolutions three orders of magnitude smaller than are available for typically used TEM imaging detectors are possible. Our experiments have shown that energy deposition of the primary electrons in the hybrid pixel detector limits the overall temporal resolution. Through adjustment of user specifiable thresholds or the use of charge summing mode, we have obtained images composed from summing 10,000s frames containing single electron events to achieve temporal resolution less than 100ns. We propose that this capability can be directly applied to studying repeatable material dynamic processes but also to implement low-dose imaging schemes in scanning transmission electron microscopy.
We report the first experimental demonstration of an electrostatic electron orbital angular momentum (OAM) sorter, which can be used to analyze the OAM states of electrons in a transmission electron microscope. We verify the sorter functionality for several electron beams possessing different superpositions of OAM states, and use it to record the electron beams OAM spectra. Our current electrostatic OAM sorter has an OAM resolution of 2 in the units of h/bar - the reduced Planck constant. It is expected to increase the OAM resolution of the sorter to the optimal resolution of 1 in the future via fine control of the sorting phase elements.
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