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Register a new userGlobally adaptive quantile regression with ultra-high dimensional data
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Added by
Qi Zheng
Publication date
2015
fields
Mathematical Statistics
and research's language is
English
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Quantile regression has become a valuable tool to analyze heterogeneous covaraite-response associations that are often encountered in practice. The development of quantile regression methodology for high-dimensional covariates primarily focuses on examination of model sparsity at a single or multiple quantile levels, which are typically pre-specified ad hoc by the users. The resulting models may be sensitive to the specific choices of the quantile levels, leading to difficulties in interpretation and erosion of confidence in the results. In this article, we propose a new penalization framework for quantile regression in the high-dimensional setting. We employ adaptive L1 penalties, and more importantly, propose a uniform selector of the tuning parameter for a set of quantile levels to avoid some of the potential problems with model selection at individual quantile levels. Our proposed approach achieves consistent shrinkage of regression quantile estimates across a continuous range of quantiles levels, enhancing the flexibility and robustness of the existing penalized quantile regression methods. Our theoretical results include the oracle rate of uniform convergence and weak convergence of the parameter estimators. We also use numerical studies to confirm our theoretical findings and illustrate the practical utility of our proposal
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Credible counterfactual analysis requires high-dimensional controls. This paper considers estimation and inference for heterogeneous counterfactual effects with high-dimensional data. We propose a novel doubly robust score for double/debiased estimation and inference for the unconditional quantile regression (Firpo, Fortin, and Lemieux, 2009) as a measure of heterogeneous counterfactual marginal effects. We propose a multiplier bootstrap inference for the Lasso double/debiased estimator, and develop asymptotic theories to guarantee that the bootstrap works. Simulation studies support our theories. Applying the proposed method to Job Corps survey data, we find that i) marginal effects of counterfactually extending the duration of the exposure to the Job Corps program are globally positive across quantiles regardless of definitions of the treatment and outcome variables, and that ii) these counterfactual effects are larger for higher potential earners than lower potential earners regardless of whether we define the outcome as the level or its logarithm.
With the availability of high dimensional genetic biomarkers, it is of interest to identify heterogeneous effects of these predictors on patients survival, along with proper statistical inference. Censored quantile regression has emerged as a powerful tool for detecting heterogeneous effects of covariates on survival outcomes. To our knowledge, there is little work available to draw inference on the effects of high dimensional predictors for censored quantile regression. This paper proposes a novel procedure to draw inference on all predictors within the framework of global censored quantile regression, which investigates covariate-response associations over an interval of quantile levels, instead of a few discrete values. The proposed estimator combines a sequence of low dimensional model estimates that are based on multi-sample splittings and variable selection. We show that, under some regularity conditions, the estimator is consistent and asymptotically follows a Gaussian process indexed by the quantile level. Simulation studies indicate that our procedure can properly quantify the uncertainty of the estimates in high dimensional settings. We apply our method to analyze the heterogeneous effects of SNPs residing in lung cancer pathways on patients survival, using the Boston Lung Cancer Survival Cohort, a cancer epidemiology study on the molecular mechanism of lung cancer.
This paper develops a novel spatial quantile function-on-scalar regression model, which studies the conditional spatial distribution of a high-dimensional functional response given scalar predictors. With the strength of both quantile regression and copula modeling, we are able to explicitly characterize the conditional distribution of the functional or image response on the whole spatial domain. Our method provides a comprehensive understanding of the effect of scalar covariates on functional responses across different quantile levels and also gives a practical way to generate new images for given covariate values. Theoretically, we establish the minimax rates of convergence for estimating coefficient functions under both fixed and random designs. We further develop an efficient primal-dual algorithm to handle high-dimensional image data. Simulations and real data analysis are conducted to examine the finite-sample performance.
$ell_1$-penalized quantile regression is widely used for analyzing high-dimensional data with heterogeneity. It is now recognized that the $ell_1$-penalty introduces non-negligible estimation bias, while a proper use of concave regularization may lead to estimators with refined convergence rates and oracle properties as the signal strengthens. Although folded concave penalized $M$-estimation with strongly convex loss functions have been well studied, the extant literature on quantile regression is relatively silent. The main difficulty is that the quantile loss is piecewise linear: it is non-smooth and has curvature concentrated at a single point. To overcome the lack of smoothness and strong convexity, we propose and study a convolution-type smoothed quantile regression with iteratively reweighted $ell_1$-regularization. The resulting smoothed empirical loss is twice continuously differentiable and (provably) locally strongly convex with high probability. We show that the iteratively reweighted $ell_1$-penalized smoothed quantile regression estimator, after a few iterations, achieves the optimal rate of convergence, and moreover, the oracle rate and the strong oracle property under an almost necessary and sufficient minimum signal strength condition. Extensive numerical studies corroborate our theoretical results.
In this paper, we consider a high-dimensional quantile regression model where the sparsity structure may differ between two sub-populations. We develop $ell_1$-penalized estimators of both regression coefficients and the threshold parameter. Our penalized estimators not only select covariates but also discriminate between a model with homogeneous sparsity and a model with a change point. As a result, it is not necessary to know or pretest whether the change point is present, or where it occurs. Our estimator of the change point achieves an oracle property in the sense that its asymptotic distribution is the same as if the unknown active sets of regression coefficients were known. Importantly, we establish this oracle property without a perfect covariate selection, thereby avoiding the need for the minimum level condition on the signals of active covariates. Dealing with high-dimensional quantile regression with an unknown change point calls for a new proof technique since the quantile loss function is non-smooth and furthermore the corresponding objective function is non-convex with respect to the change point. The technique developed in this paper is applicable to a general M-estimation framework with a change point, which may be of independent interest. The proposed methods are then illustrated via Monte Carlo experiments and an application to tipping in the dynamics of racial segregation.
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