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Sine-Gordon Solitons, Kinks and Breathers as Physical Models of Nonlinear Excitations in Living Cellular Structures

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 Added by Tijana Ivancevic
 Publication date 2013
  fields Biology Physics
and research's language is English




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Nonlinear space-time dynamics, defined in terms of celebrated solitonic equations, brings indispensable tools for understanding, prediction and control of complex behaviors in both physical and life sciences. In this paper, we review sine-Gordon solitons, kinks and breathers as models of nonlinear excitations in complex systems in physics and in living cellular structures, both intra-cellular (DNA, protein folding and microtubules) and inter-cellular (neural impulses and muscular contractions). Key words: Sine-Gordon solitons, kinks and breathers, DNA, Protein folding, Microtubules, Neural conduction, Muscular contraction



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111 - Niurka R. Quintero , 2000
We analyze the diffusive motion of kink solitons governed by the thermal sine-Gordon equation. We analytically calculate the correlation function of the position of the kink center as well as the diffusion coefficient, both up to second-order in temperature. We find that the kink behavior is very similar to that obtained in the overdamped limit: There is a quadratic dependence on temperature in the diffusion coefficient that comes from the interaction among the kink and phonons, and the average value of the wave function increases with $sqrt{t}$ due to the variance of the centers of individual realizations and not due to kink distortions. These analytical results are fully confirmed by numerical simulations.
We consider the existence and spectral stability of static multi-kink structures in the discrete sine-Gordon equation, as a representative example of the family of discrete Klein-Gordon models. The multi-kinks are constructed using Lins method from an alternating sequence of well-separated kink and antikink solutions. We then locate the point spectrum associated with these multi-kink solutions by reducing the spectral problem to a matrix equation. For an $m$-structure multi-kink, there will be $m$ eigenvalues in the point spectrum near each eigenvalue of the primary kink, and, as long as the spectrum of the primary kink is imaginary, the spectrum of the multi-kink will be as well. We obtain analytic expressions for the eigenvalues of a multi-kink in terms of the eigenvalues and corresponding eigenfunctions of the primary kink, and these are in very good agreement with numerical results. We also perform numerical time-stepping experiments on perturbations of multi-kinks, and the outcomes of these simulations are interpreted using the spectral results.
111 - B. Piette , W.J. Zakrzewski 2007
We analyse the scattering of sine-Gordon breathers on a square potential well. We show that the scattering process depends not only on the vibration frequency of the breather and its incoming speed but also on its phase as well as the depth and width of the well. We show that the breather can pass through the well and exit with a speed different, sometime larger, from the initial one. It can also be trapped and very slowly decay inside the well or bounce out of the well and go back to where it came from. We also show that the breather can split into a kink and an anti-kink pair when it hits the well.
340 - J. Honer , U. Weiss 2010
We study a conjecture by Fendley, Ludwig and Saleur for the nonlinear conductance in the boundary sine-Gordon model. They have calculated the perturbative series of twisted partition functions, which require particular (unphysical) imaginary values of the bias, by applying the tools of Jack symmetric functions to the log-sine Coulomb gas on a circle. We have analyzed the conjectured relation between the analytically continued free energy and the nonlinear conductance in various limits. We confirm the conjecture for weak and strong tunneling, in the classical regime, and in the zero temperature limit. We also shed light on this special variant of the ${rm Im} F$-method and compare it with the real-time Keldysh approach. In addition, we address the issue of quantum statistical fluctuations.
In this work we analyze the possibility that soliton dynamics in a simple nonlinear model allows functionally relevant predictions of the behaviour of DNA. This suggestion was first put forward by Salerno [Phys. Rev. A, vol. 44, p. 5292 (1991)] by showing results indicating that sine-Gordon kinks were set in motion at certain regions of a DNA sequence that include promoters. We revisit that system and show that the observed behaviour has nothing to do with promoters; on the contrary, it originates from the bases at the boundary, which are not part of the studied genome. We explain this phenomenology in terms of an effective potential for the kink center. This is further extended to disprove recent claims that the dynamics of kinks [Lenholm and Hornquist, Physica D, vol. 177, p. 233 (2003)] or breathers [Bashford, J. Biol. Phys., vol. 32, p. 27 (2006)] has functional significance. We conclude that no such information can be extracted from this simple nonlinear model or its associated effective potential.
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