The researcher's responsibility is to protect the interests and the physical, psychological
andmentalintegrity of the research participants. The aim of this article is: 1- To give some information
about the basic principles of research ethics. 2- T
o prepare guidelines for human subject research
protection at the colleges of dental medicine in Syria. Conclusions: principles of ethics in dental research
and informed consent are still not clear in Syria; there is a need to ethical research committees and ethical
research guidelines in dental colleges in Syria.