There are a lot of studies with conflicting results about the correlation between blood
levels of vitamin D and lipid profile (total cholesterol, LDLc, HDLc) and the effect of
treatment with vitamin D supplements on it. This study aimed to investig
ate the effect of
vitamin D and calcium supplements on lipid profile.
This study included 59 volunteers who received these supplements for prevention of
osteoporosis as a prescription from orthopedic doctors between 11/2016 to 1/2018. The
average of age was 49±8 years. The plasma values of TC, LDLc, HDLc were measured
using enzymatic colorimetric method ( Biosystems kits ) in Tishreen hospital before
treatment and after two months. The results were analyzed by T-Student test, and P value
<0.05 was considered significant. The mean plasma levels of LDLc before treatment were
(100.983 ±28.36) mg/dl, and after two months of treatment were (102.249±27.478) mg/dl,
and the difference was not significant. The mean plasma levels of HDLc before treatment
were (68.056 ±14.369) mg/dl and after two months of treatment were (62.715 ± 14.39)
mg/dl, and the difference was significant. We advise to measure plasma lipid levels during
treatment with these supplements depending on the changes that observed in this study.
