Investigation The Expression of Chemokine Receptor CXCR4 in Head and Neck Squamous Cell Carcinoma-metastiatic lymph Nodes and Compare It with its Primary Tumor (clinical immunohistochemistry study)

this study Aimes to Investigate CXCR4 expression in primary head and neck squamous cell carcinomas tumors in all clinical stages and histological grades, then compare it with control normal oral epithelial tissues. Compare metastatic lymph nodes CXCR4 expression with their primary HNSCC tumors at high stages which associated with metastatic lymph nodes.