T cells express co-stimulatory molecules on their surfaces in both normal and
pathologic settings; however, the possibility that expression of these co-stimulators may enable individual
T cells to co-stimulate themselves has not been investigated.
This study aims at assessing the possible potentiation of T cells activation and proliferation both in vitro
and in vivo via enforced B7-1 expression on T lymphocytes using a non-genetic approach, i.e. cell painting,
that comprises binding of recombinant B7-1 to plasma membrane-anchored palmitoylated protein A.
