اشترك بالحزمة الذهبية واحصل على وصول غير محدود شمرا أكاديميا
تسجيل مستخدم جديدOptical funnel to guide and focus virus particles for X-ray laser imaging
315
0
0.0
(
0
)
اسأل ChatGPT حول البحث
ﻻ يوجد ملخص باللغة العربية
The need for precise manipulation of nanoparticles in gaseous or near-vacuum environments is encountered in many studies that include aerosol morphology, nanodroplet physics, nanoscale optomechanics, and biomolecular physics. Photophoretic forces, whereby momentum exchange between a particle and surrounding gas is induced with optical light, were recently shown to be a robust means of trapping and manipulating nanoparticles in air. We previously proposed a photophoretic optical funnel concept for the delivery of bioparticles to the focus of an x-ray free-electron laser (XFEL) beam for femtosecond x-ray diffractive imaging. Here, we describe the formation of a high-aspect-ratio optical funnel and provide a first experimental demonstration of this concept by transversely compressing and concentrating a high-speed beam of aerosolized viruses by a factor of three in a low-pressure environment. These results pave the way toward improved sample delivery efficiency for XFEL imaging experiments as well as other forms of imaging and spectroscopy.
قيم البحث
اقرأ أيضاً
A laser beam propagating to a remote target through atmospheric turbulence acquires intensity fluctuations. If the target is cooperative and provides a coherent return beam, the phase measured near the beam transmitter and adaptive optics can, in pri
nciple, correct these fluctuations. Generally, however, the target is uncooperative. In this case, we show that an incoherent return from the target can be used instead. Using the principle of reciprocity, we derive a novel relation between the field at the target and the reflected field at a detector. We simulate an adaptive optics system that utilizes this relation to focus a beam through atmospheric turbulence onto the incoherent surface.
We present a new method for the generation of atmospheric turbulence phase screens based on the frequency shift property of the Fourier transform. This method produces low spatial frequency distortions without additional computation time penalties as
sociated with methods using subharmonic subgrids. It is demonstrated that for simulations of atmospheric turbulence with finite outer scales, the performance of our method with respect to the statistical phase structure function of the screen meets or exceeds other methods with respect to agreement with theory. We outline small-scale accuracy issues associated with modelling non-Kolmogorov spectral power laws using existing techniques, and propose a solution. For simulations of long-range propagation through atmospheric optical turbulence, our method provides various advantages over standard methods.
We put forward a co-axial pump(optical)-probe(X-rays) experimental concept and show performance of the optical component. A Bessel beam generator with a central 100 micrometers-diameter hole (on the optical axis) was fabricated using femtosecond (fs)
laser structuring inside a silica plate. This flat-axicon optical element produces a needle-like axial intensity distribution which can be used for the optical pump pulse. The fs-X-ray free electron laser (X-FEL) beam of sub-1 micrometer diameter can be introduced through the central hole along the optical axis onto a target as a probe. Different realisations of optical pump are discussed. Such optical elements facilitate alignment of ultra-short fs-pulses in space and time and can be used in light-matter interaction experiments at extreme energy densities on the surface and in the volume of targets. Full advantage of ultra-short 10 fs X-FEL probe pulses with fs-pump(optical) opens an unexplored temporal dimension of phase transitions and the fastest laser-induced rates of material heating and quenching. A wider field of applications of fs-laser-enabled structuring of materials and design of specific optical elements for astrophotonics is presented.
Electromagnetic stimulation of energetic materials provides a noninvasive and nondestructive tool for detecting and identifying explosives. We combine structural information based on X-ray computed tomography, experimental dielectric data, and electr
omagnetic full-wave simulations, to study microscale electromagnetic heating of realistic three-dimensional heterogeneous explosives. We analyze the formation of electromagnetic hot spots and thermal gradients in the explosive-binder meso-structures, and compare the heating rate for various binder systems.
The superposition of a Gaussian mode and a Laguerre-Gauss mode with $ell=0,p eq0$ generates the so-called bottle beam: a dark focus surrounded by a bright region. In this paper, we theoretically explore the use of bottle beams as an optical trap for
dielectric spheres with a refractive index smaller than that of their surrounding medium. The forces acting on a small particle are derived within the dipole approximation and used to simulate the Brownian motion of the particle in the trap. The intermediate regime of particle size is studied numerically and it is found that stable trapping of larger dielectric particles is also possible. Based on the results of the intermediate regime analysis, an experiment aimed at trapping living organisms in the dark focus of a bottle beam is proposed.
سجل دخول لتتمكن من نشر تعليقات
التعليقات
جاري جلب التعليقات
سجل دخول لتتمكن من متابعة معايير البحث التي قمت باختيارها
