ترغب بنشر مسار تعليمي؟ اضغط هنا

Modeling epidemics on adaptively evolving networks: a data-mining perspective

196   0   0.0 ( 0 )
 نشر من قبل Alexander Holiday
 تاريخ النشر 2015
  مجال البحث علم الأحياء فيزياء
والبحث باللغة English




اسأل ChatGPT حول البحث

The exploration of epidemic dynamics on dynamically evolving (adaptive) networks poses nontrivial challenges to the modeler, such as the determination of a small number of informative statistics of the detailed network state (that is, a few good observables) that usefully summarize the overall (macroscopic, systems level) behavior. Trying to obtain reduced, small size, accurate models in terms of these few statistical observables - that is, coarse-graining the full network epidemic model to a small but useful macroscopic one - is even more daunting. Here we describe a data-based approach to solving the first challenge: the detection of a few informative collective observables of the detailed epidemic dynamics. This will be accomplished through Diffusion Maps, a recently developed data-mining technique. We illustrate the approach through simulations of a simple mathematical model of epidemics on a network: a model known to exhibit complex temporal dynamics. We will discuss potential extensions of the approach, as well as possible shortcomings.



قيم البحث

اقرأ أيضاً

154 - Joel C. Miller , Tony TIng 2020
We provide a description of the Epidemics on Networks (EoN) python package designed for studying disease spread in static networks. The package consists of over $100$ methods available for users to perform stochastic simulation of a range of differen t processes including SIS and SIR disease, and generic simple or comlex contagions.
We investigate social networks of characters found in cultural works such as novels and films. These character networks exhibit many of the properties of complex networks such as skewed degree distribution and community structure, but may be of relat ively small order with a high multiplicity of edges. Building on recent work of beveridge, we consider graph extraction, visualization, and network statistics for three novels: Twilight by Stephanie Meyer, Steven Kings The Stand, and J.K. Rowlings Harry Potter and the Goblet of Fire. Coupling with 800 character networks from films found in the http://moviegalaxies.com/ database, we compare the data sets to simulations from various stochastic complex networks models including random graphs with given expected degrees (also known as the Chung-Lu model), the configuration model, and the preferential attachment model. Using machine learning techniques based on motif (or small subgraph) counts, we determine that the Chung-Lu model best fits character networks and we conjecture why this may be the case.
Human mobility is a key component of large-scale spatial-transmission models of infectious diseases. Correctly modeling and quantifying human mobility is critical for improving epidemic control policies, but may be hindered by incomplete data in some regions of the world. Here we explore the opportunity of using proxy data or models for individual mobility to describe commuting movements and predict the diffusion of infectious disease. We consider three European countries and the corresponding commuting networks at different resolution scales obtained from official census surveys, from proxy data for human mobility extracted from mobile phone call records, and from the radiation model calibrated with census data. Metapopulation models defined on the three countries and integrating the different mobility layers are compared in terms of epidemic observables. We show that commuting networks from mobile phone data well capture the empirical commuting patterns, accounting for more than 87% of the total fluxes. The distributions of commuting fluxes per link from both sources of data - mobile phones and census - are similar and highly correlated, however a systematic overestimation of commuting traffic in the mobile phone data is observed. This leads to epidemics that spread faster than on census commuting networks, however preserving the order of infection of newly infected locations. Match in the epidemic invasion pattern is sensitive to initial conditions: the radiation model shows higher accuracy with respect to mobile phone data when the seed is central in the network, while the mobile phone proxy performs better for epidemics seeded in peripheral locations. Results suggest that different proxies can be used to approximate commuting patterns across different resolution scales in spatial epidemic simulations, in light of the desired accuracy in the epidemic outcome under study.
We study several bayesian inference problems for irreversible stochastic epidemic models on networks from a statistical physics viewpoint. We derive equations which allow to accurately compute the posterior distribution of the time evolution of the s tate of each node given some observations. At difference with most existing methods, we allow very general observation models, including unobserved nodes, state observations made at different or unknown times, and observations of infection times, possibly mixed together. Our method, which is based on the Belief Propagation algorithm, is efficient, naturally distributed, and exact on trees. As a particular case, we consider the problem of finding the zero patient of a SIR or SI epidemic given a snapshot of the state of the network at a later unknown time. Numerical simulations show that our method outperforms previous ones on both synthetic and real networks, often by a very large margin.
182 - Rick Durrett , Dong Yao 2020
The evoSIR model is a modification of the usual SIR process on a graph $G$ in which $S-I$ connections are broken at rate $rho$ and the $S$ connects to a randomly chosen vertex. The evoSI model is the same as evoSIR but recovery is impossible. In an u ndergraduate project at Duke the critical value for evoSIR was computed and simulations showed that when $G$ is an ErdH os-Renyi graph with mean degree 5, the system has a discontinuous phase transition, i.e., as the infection rate $lambda$ decreases to $lambda_c$, the fraction of individuals infected during the epidemic does not converge to 0. In this paper we study evoSI dynamics on graphs generated by the configuration model. We show that there is a quantity $Delta$ determined by the first three moments of the degree distribution, so that the phase transition is discontinuous if $Delta>0$ and continuous if $Delta<0$.
التعليقات
جاري جلب التعليقات جاري جلب التعليقات
سجل دخول لتتمكن من متابعة معايير البحث التي قمت باختيارها
mircosoft-partner

هل ترغب بارسال اشعارات عن اخر التحديثات في شمرا-اكاديميا