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We investigate the protein expression pattern of the lamB gene in Escherichia coli LE392. The gene product LamB is an important membrane protein for maltose transport into cells but it is also exploited by bacteriophage lambda for infection. Although our bacterial population is clonal, stochastic gene expression leads to a majority population with a large receptor number and a minority population with a small receptor number. We find that the LamB receptor distribution p(n) of the small-n population is scale invariant with the exponent depending on growth conditions. A heuristic model is proposed that relates the observed exponent to the protein production rate.
The complex dynamics of intracellular calcium regulates cellular responses to information encoded in extracellular signals. Here, we study the encoding of these external signals in the context of the Li-Rinzel model. We show that by control of biophy
We introduce a persistent random walk model with finite velocity and self-reinforcing directionality, which explains how exponentially distributed runs self-organize into truncated Levy walks observed in active intracellular transport by Chen et. al.
The novel coronavirus SARS-CoV-2 has resulted in a global pandemic with worldwide 6-digital infection rates and thousands death tolls daily. Enormeous effords are undertaken to achieve high coverage of immunization in order to reach herd immunity to
We present a version of Kleibers scaling law for fetus and placenta.
Dangerous damage to mitochondrial DNA (mtDNA) can be ameliorated during mammalian development through a highly debated mechanism called the mtDNA bottleneck. Uncertainty surrounding this process limits our ability to address inherited mtDNA diseases.