اشترك بالحزمة الذهبية واحصل على وصول غير محدود شمرا أكاديميا
تسجيل مستخدم جديدBrownian motion, ionic flux, catalytic reaction and heterogeneous nucleation in biological systems
71
0
0.0
(
0
)
اسأل ChatGPT حول البحث
ﻻ يوجد ملخص باللغة العربية
A model to describe the arising of new structures in an initial homogeneous biological system is proposed. The essay is motivated by the intention to work on a non-equilibrium situation grouping together several mechanisms and processes as: catalytic reactions on a surface, diffusion, stimulated migration and selective heterogeneous reaction. A model for morphogenesis in early embryos is developed on two basic assumptions; (i) the existence of an electrified surface that defines the shape (form) of the growing structure and (ii) a mechanism to select morphogens (ions or free radicals) from an initially homogeneous medium. The homogeneity is broke when an electric potential arise between different parcels of the system, triggering a complex dynamic that drive the development of material deposits into localized regions of the space. The evolution of the deposits is described by a stochastic formalism allowing for analytical expressions relating macroscopic.
قيم البحث
اقرأ أيضاً
We analyse the effects of environmental noise in three different biological systems: (i) mating behaviour of individuals of emph{Nezara viridula} (L.) (Heteroptera Pentatomidae); (ii) polymer translocation in crowded solution; (iii) an ecosystem desc
ribed by a Verhulst model with a multiplicative L{e}vy noise.
In this paper we briefly discuss the necessity of using quantum mechanics as a fundamental theory applicable to some key functional aspects of biological systems. This is especially relevant to three important parts of a neuron in the human brain, na
mely the cell membrane, microtubules (MT) and ion channels. We argue that the recently published papers criticizing the use of quantum theory in these systems are not convincing.
Even in the steady-state, the number of biomolecules in living cells fluctuates dynamically; and the frequency spectrum of this chemical fluctuation carries valuable information about the mechanism and the dynamics of the intracellular reactions crea
ting these biomolecules. Although recent advances in single-cell experimental techniques enable the direct monitoring of the time-traces of the biological noise in each cell, the development of the theoretical tools needed to extract the information encoded in the stochastic dynamics of intracellular chemical fluctuation is still in its adolescence. Here, we present a simple and general equation that relates the power-spectrum of the product number fluctuation to the product lifetime and the reaction dynamics of the product creation process. By analyzing the time traces of the protein copy number using this theory, we can extract the power spectrum of the mRNA number, which cannot be directly measured by currently available experimental techniques. From the power spectrum of the mRNA number, we can further extract quantitative information about the transcriptional regulation dynamics. Our power spectrum analysis of gene expression noise is demonstrated for the gene network model of luciferase expression under the control of the Bmal 1a promoter in mouse fibroblast cells. Additionally, we investigate how the non-Poisson reaction dynamics and the cell-to-cell heterogeneity in transcription and translation affect the power-spectra of the mRNA and protein number.
We study the twirling semigroups of (super)operators, namely, certain quantum dynamical semigroups that are associated, in a natural way, with the pairs formed by a projective representation of a locally compact group and a convolution semigroup of p
robability measures on this group. The link connecting this class of semigroups of operators with (classical) Brownian motion is clarified. It turns out that every twirling semigroup associated with a finite-dimensional representation is a random unitary semigroup, and, conversely, every random unitary semigroup arises as a twirling semigroup. Using standard tools of the theory of convolution semigroups of measures and of convex analysis, we provide a complete characterization of the infinitesimal generator of a twirling semigroup associated with a finite-dimensional unitary representation of a Lie group.
We solve the model of N quantum Brownian oscillators linearly coupled to an environment of quantum oscillators at finite temperature, with no extra assumptions about the structure of the system-environment coupling. Using a compact phase-space formal
ism, we give a rather quick and direct derivation of the master equation and its solutions for general spectral functions and arbitrary temperatures. Since our framework is intrinsically nonperturbative, we are able to analyze the entanglement dynamics of two oscillators coupled to a common scalar field in previously unexplored regimes, such as off resonance and strong coupling.
سجل دخول لتتمكن من نشر تعليقات
التعليقات
جاري جلب التعليقات
سجل دخول لتتمكن من متابعة معايير البحث التي قمت باختيارها
