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Length Regulation Drives Self-Organization in Filament-Motor Mixtures

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 نشر من قبل Fridtjof Brauns
 تاريخ النشر 2021
  مجال البحث فيزياء
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Cytoskeletal networks form complex intracellular structures. Here we investigate a minimal model for filament-motor mixtures in which motors act as depolymerases and thereby regulate filament length. Combining agent-based simulations and hydrodynamic equations, we show that resource-limited length regulation drives the formation of filament clusters despite the absence of mechanical interactions between filaments. Even though the orientation of individual remains fixed, collective filament orientation emerges in the clusters, aligned orthogonal to their interfaces.

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