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The loss function of an unsupervised multimodal image registration framework has two terms, i.e., a metric for similarity measure and regularization. In the deep learning era, researchers proposed many approaches to automatically learn the similarity metric, which has been shown effective in improving registration performance. However, for the regularization term, most existing multimodal registration approaches still use a hand-crafted formula to impose artificial properties on the estimated deformation field. In this work, we propose a unimodal cyclic regularization training pipeline, which learns task-specific prior knowledge from simpler unimodal registration, to constrain the deformation field of multimodal registration. In the experiment of abdominal CT-MR registration, the proposed method yields better results over conventional regularization methods, especially for severely deformed local regions.
We describe an adversarial learning approach to constrain convolutional neural network training for image registration, replacing heuristic smoothness measures of displacement fields often used in these tasks. Using minimally-invasive prostate cancer
One of the fundamental challenges in supervised learning for multimodal image registration is the lack of ground-truth for voxel-level spatial correspondence. This work describes a method to infer voxel-level transformation from higher-level correspo
Spatially aligning medical images from different modalities remains a challenging task, especially for intraoperative applications that require fast and robust algorithms. We propose a weakly-supervised, label-driven formulation for learning 3D voxel
Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image registration. Howeve
Deformable image registration between Computed Tomography (CT) images and Magnetic Resonance (MR) imaging is essential for many image-guided therapies. In this paper, we propose a novel translation-based unsupervised deformable image registration met