ترغب بنشر مسار تعليمي؟ اضغط هنا

Adversarial Robust Training of Deep Learning MRI Reconstruction Models

82   0   0.0 ( 0 )
 نشر من قبل Francesco Caliva PhD
 تاريخ النشر 2020
والبحث باللغة English




اسأل ChatGPT حول البحث

Deep Learning (DL) has shown potential in accelerating Magnetic Resonance Image acquisition and reconstruction. Nevertheless, there is a dearth of tailored methods to guarantee that the reconstruction of small features is achieved with high fidelity. In this work, we employ adversarial attacks to generate small synthetic perturbations, which are difficult to reconstruct for a trained DL reconstruction network. Then, we use robust training to increase the networks sensitivity to these small features and encourage their reconstruction. Next, we investigate the generalization of said approach to real world features. For this, a musculoskeletal radiologist annotated a set of cartilage and meniscal lesions from the knee Fast-MRI dataset, and a classification network was devised to assess the reconstruction of the features. Experimental results show that by introducing robust training to a reconstruction network, the rate of false negative features (4.8%) in image reconstruction can be reduced. These results are encouraging, and highlight the necessity for attention to this problem by the image reconstruction community, as a milestone for the introduction of DL reconstruction in clinical practice. To support further research, we make our annotations and code publicly available at https://github.com/fcaliva/fastMRI_BB_abnormalities_annotation.



قيم البحث

اقرأ أيضاً

Deep learning based generative adversarial networks (GAN) can effectively perform image reconstruction with under-sampled MR data. In general, a large number of training samples are required to improve the reconstruction performance of a certain mode l. However, in real clinical applications, it is difficult to obtain tens of thousands of raw patient data to train the model since saving k-space data is not in the routine clinical flow. Therefore, enhancing the generalizability of a network based on small samples is urgently needed. In this study, three novel applications were explored based on parallel imaging combined with the GAN model (PI-GAN) and transfer learning. The model was pre-trained with public Calgary brain images and then fine-tuned for use in (1) patients with tumors in our center; (2) different anatomies, including knee and liver; (3) different k-space sampling masks with acceleration factors (AFs) of 2 and 6. As for the brain tumor dataset, the transfer learning results could remove the artifacts found in PI-GAN and yield smoother brain edges. The transfer learning results for the knee and liver were superior to those of the PI-GAN model trained with its own dataset using a smaller number of training cases. However, the learning procedure converged more slowly in the knee datasets compared to the learning in the brain tumor datasets. The reconstruction performance was improved by transfer learning both in the models with AFs of 2 and 6. Of these two models, the one with AF=2 showed better results. The results also showed that transfer learning with the pre-trained model could solve the problem of inconsistency between the training and test datasets and facilitate generalization to unseen data.
Retrospectively gated cine (retro-cine) MRI is the clinical standard for cardiac functional analysis. Deep learning (DL) based methods have been proposed for the reconstruction of highly undersampled MRI data and show superior image quality and magni tude faster reconstruction time than CS-based methods. Nevertheless, it remains unclear whether DL reconstruction is suitable for cardiac function analysis. To address this question, in this study we evaluate and compare the cardiac functional values (EDV, ESV and EF for LV and RV, respectively) obtained from highly accelerated MRI acquisition using DL based reconstruction algorithm (DL-cine) with values from CS-cine and conventional retro-cine. To the best of our knowledge, this is the first work to evaluate the cine MRI with deep learning reconstruction for cardiac function analysis and compare it with other conventional methods. The cardiac functional values obtained from cine MRI with deep learning reconstruction are consistent with values from clinical standard retro-cine MRI.
In spite of its extensive adaptation in almost every medical diagnostic and examinatorial application, Magnetic Resonance Imaging (MRI) is still a slow imaging modality which limits its use for dynamic imaging. In recent years, Parallel Imaging (PI) and Compressed Sensing (CS) have been utilised to accelerate the MRI acquisition. In clinical settings, subsampling the k-space measurements during scanning time using Cartesian trajectories, such as rectilinear sampling, is currently the most conventional CS approach applied which, however, is prone to producing aliased reconstructions. With the advent of the involvement of Deep Learning (DL) in accelerating the MRI, reconstructing faithful images from subsampled data became increasingly promising. Retrospectively applying a subsampling mask onto the k-space data is a way of simulating the accelerated acquisition of k-space data in real clinical setting. In this paper we compare and provide a review for the effect of applying either rectilinear or radial retrospective subsampling on the quality of the reconstructions outputted by trained deep neural networks. With the same choice of hyper-parameters, we train and evaluate two distinct Recurrent Inference Machines (RIMs), one for each type of subsampling. The qualitative and quantitative results of our experiments indicate that the model trained on data with radial subsampling attains higher performance and learns to estimate reconstructions with higher fidelity paving the way for other DL approaches to involve radial subsampling.
Fast data acquisition in Magnetic Resonance Imaging (MRI) is vastly in demand and scan time directly depends on the number of acquired k-space samples. The data-driven methods based on deep neural networks have resulted in promising improvements, com pared to the conventional methods, in image reconstruction algorithms. The connection between deep neural network and Ordinary Differential Equation (ODE) has been observed and studied recently. The studies show that different residual networks can be interpreted as Euler discretization of an ODE. In this paper, we propose an ODE-based deep network for MRI reconstruction to enable the rapid acquisition of MR images with improved image quality. Our results with undersampled data demonstrate that our method can deliver higher quality images in comparison to the reconstruction methods based on the standard UNet network and Residual network.
Purpose: Although recent deep energy-based generative models (EBMs) have shown encouraging results in many image generation tasks, how to take advantage of the self-adversarial cogitation in deep EBMs to boost the performance of Magnetic Resonance Im aging (MRI) reconstruction is still desired. Methods: With the successful application of deep learning in a wide range of MRI reconstruction, a line of emerging research involves formulating an optimization-based reconstruction method in the space of a generative model. Leveraging this, a novel regularization strategy is introduced in this article which takes advantage of self-adversarial cogitation of the deep energy-based model. More precisely, we advocate for alternative learning a more powerful energy-based model with maximum likelihood estimation to obtain the deep energy-based information, represented as image prior. Simultaneously, implicit inference with Langevin dynamics is a unique property of re-construction. In contrast to other generative models for reconstruction, the proposed method utilizes deep energy-based information as the image prior in reconstruction to improve the quality of image. Results: Experiment results that imply the proposed technique can obtain remarkable performance in terms of high reconstruction accuracy that is competitive with state-of-the-art methods, and does not suffer from mode collapse. Conclusion: Algorithmically, an iterative approach was presented to strengthen EBM training with the gradient of energy network. The robustness and the reproducibility of the algorithm were also experimentally validated. More importantly, the proposed reconstruction framework can be generalized for most MRI reconstruction scenarios.
التعليقات
جاري جلب التعليقات جاري جلب التعليقات
سجل دخول لتتمكن من متابعة معايير البحث التي قمت باختيارها
mircosoft-partner

هل ترغب بارسال اشعارات عن اخر التحديثات في شمرا-اكاديميا