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تسجيل مستخدم جديدMechanistic Modelling of Chromatin Folding to Understand Function
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Experimental approaches have been applied to address questions in understanding three-dimensional chromatin organisation and function. As datasets increase in size and complexity, it becomes a challenge to reach a mechanistic interpretation of experimental results. Polymer simulations and mechanistic modelling have been applied to explain experimental observations, and the links to different aspects of genome function. Here, we provide a guide for biologists, explaining different simulation approaches and the contexts in which they have been used.
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