ترغب بنشر مسار تعليمي؟ اضغط هنا

Detecting and tracking bacteria with quantum light

173   0   0.0 ( 0 )
 نشر من قبل Stefano Pirandola
 تاريخ النشر 2020
  مجال البحث فيزياء
والبحث باللغة English




اسأل ChatGPT حول البحث

The field of quantum sensing aims at improving the detection and estimation of classical parameters that are encoded in physical systems by resorting to quantum sources of light and quantum detection strategies. The same approach can be used to improve the current classical measurements that are performed on biological systems. Here we consider the scenario of two bacteria (E. coli and Salmonella) growing in a Luria Bertani broth and monitored by classical spectrophotometers. Their concentration can be related to the optical transmissivity via the Beer-Lambert-Bouguers law and their growth curves can be described by means of Gompertz functions. Starting from experimental data points, we extrapolate the growth curves of the two bacteria and we study the theoretical performance that would be achieved with a quantum setup. In particular, we discuss how the bacterial growth can, in principle, be tracked by irradiating the samples with orders of magnitude fewer photons, identifying the clear superiority of quantum light in the early stages of growth. We then show the superiority and the limits of quantum resources in two basic tasks: (i) the early detection of bacterial growth and (ii) the early discrimination between two bacteria species.



قيم البحث

اقرأ أيضاً

External control of the swimming speed of `active particles can be used to self assemble designer structures in situ on the micrometer to millimeter scale. We demonstrate such reconfigurable templated active self assembly in a fluid environment using light powered strains of Escherichia coli. The physics and biology controlling the sharpness and formation speed of patterns is investigated using a bespoke fast-responding strain.
We demonstrate a different scheme to perform optical sectioning of a sample based on the concept of induced coherence [Zou et al., Phys. Rev. Lett. 67, 318 (1991)]. This can be viewed as a different type of optical coherence tomography scheme where t he varying reflectivity of the sample along the direction of propagation of an optical beam translates into changes of the degree of first-order coherence between two beams. As a practical advantage the scheme allows probing the sample with one wavelength and measuring photons with another wavelength. In a bio-imaging scenario, this would result in a deeper penetration into the sample because of probing with longer wavelengths, while still using the optimum wavelength for detection. The scheme proposed here could achieve submicron axial resolution by making use of nonlinear parametric sources with broad spectral bandwidth emission.
Light harvesting components of photosynthetic organisms are complex, coupled, many-body quantum systems, in which electronic coherence has recently been shown to survive for relatively long time scales despite the decohering effects of their environm ents. Within this context, we analyze entanglement in multi-chromophoric light harvesting complexes, and establish methods for quantification of entanglement by presenting necessary and sufficient conditions for entanglement and by deriving a measure of global entanglement. These methods are then applied to the Fenna-Matthews-Olson (FMO) protein to extract the initial state and temperature dependencies of entanglement. We show that while FMO in natural conditions largely contains bipartite entanglement between dimerized chromophores, a small amount of long-range and multipartite entanglement exists even at physiological temperatures. This constitutes the first rigorous quantification of entanglement in a biological system. Finally, we discuss the practical utilization of entanglement in densely packed molecular aggregates such as light harvesting complexes.
Quantum properties, such as entanglement and coherence, are indispensable resources in various quantum information processing tasks. However, there still lacks an efficient and scalable way to detecting these useful features especially for high-dimen sional quantum systems. In this work, we exploit the convexity of normal samples without quantum features and design an unsupervised machine learning method to detect the presence of quantum features as anomalies. Particularly, given the task of entanglement detection, we propose a complex-valued neural network composed of pseudo-siamese network and generative adversarial net, and then train it with only separable states to construct non-linear witnesses for entanglement. It is shown via numerical examples, ranging from 2-qubit to 10-qubit systems, that our network is able to achieve high detection accuracy with above 97.5% on average. Moreover, it is capable of revealing rich structures of entanglement, such as partial entanglement among subsystems. Our results are readily applicable to the detection of other quantum resources such as Bell nonlocality and steerability, indicating that our work could provide a powerful tool to extract quantum features hidden in high-dimensional quantum data.
A thin-walled tube, e.g., a drinking straw, manifests an instability when bent by localizing the curvature change in a small region. This instability has been extensively studied since the seminal work of Brazier nearly a century ago. However, the sc enario of pressurized tubes has received much less attention. Motivated by rod-shaped bacteria such as E. coli, whose cell walls are much thinner than their radius and are subject to a substantial internal pressure, we study, theoretically, how this instability is affected by this internal pressure. In the parameter range relevant to the bacteria, we find that the internal pressure significantly postpones the onset of the instability, while the bending stiffness of the cell wall has almost no influence. This study suggests a new method to infer turgor pressure in rod-shaped bacteria from bending experiments.
التعليقات
جاري جلب التعليقات جاري جلب التعليقات
سجل دخول لتتمكن من متابعة معايير البحث التي قمت باختيارها
mircosoft-partner

هل ترغب بارسال اشعارات عن اخر التحديثات في شمرا-اكاديميا