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In some cases, the function of a lesioned area can be compensated for by another area. However, it remains unpredictable if and by which other area a lesion can be compensated. We assume that similar incoming and outgoing connections are necessary to encode the same function as the damaged region. The similarity can be measured both locally using the matching index and looking at a more global scale by non-metric multidimensional scaling (NMDS). We tested how well both measures can predict the compensating area for the loss of the visual cortex in kittens. For this case study, the global comparison of connectivity turns out to be a better method for predicting functional compensation. In future studies, the extent of the similarity between the lesioned and compensating regions might be a measure of the extent to which function can be successfully recovered.
A large body of literature has shown the substantial inter-regional functional connectivity in the mammal brain. One important property remaining un-studied is the cross-time interareal connection. This paper serves to provide a tool to characterize
During development, the mammalian brain differentiates into specialized regions with distinct functional abilities. While many factors contribute to functional specialization, we explore the effect of neuronal density on the development of neuronal i
The dynamic characteristics of functional network connectivity have been widely acknowledged and studied. Both shared and unique information has been shown to be present in the connectomes. However, very little has been known about whether and how th
Structural covariance analysis is a widely used structural MRI analysis method which characterises the co-relations of morphology between brain regions over a group of subjects. To our knowledge, little has been investigated in terms of the comparabi
In recent years, the field of neuroscience has gone through rapid experimental advances and extensive use of quantitative and computational methods. This accelerating growth has created a need for methodological analysis of the role of theory and the