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The dynamics of an SIS epidemic patch model with asymmetric connectivity matrix is analyzed. It is shown that the basic reproduction number $R_0$ is strictly decreasing with respect to the dispersal rate of the infected individuals, and the model has a unique endemic equilibrium if $R_0>1$. The asymptotic profiles of the endemic equilibrium for small dispersal rates are characterized. In particular, it is shown that the endemic equilibrium converges to a limiting disease-free equilibrium as the dispersal rate of susceptible individuals tends to zero, and the limiting disease-free equilibrium has a positive number of susceptible individuals on each low-risk patch. Moreover a sufficient and necessary condition is found to guarantee that the limiting disease-free equilibrium has no positive number of susceptible individuals on each high-risk patch. Our results extend earlier results for symmetric connectivity matrix, and we also partially solve an open problem by Allen et al. (SIAM J. Appl. Math., 67: 1283-1309, 2007).
In this paper we provide the derivation of a super compact pairwise model with only 4 equations in the context of describing susceptible-infected-susceptible (SIS) epidemic dynamics on heterogenous networks. The super compact model is based on a new
Here, we consider an SIS epidemic model where the individuals are distributed on several distinct patches. We construct a stochastic model and then prove that it converges to a deterministic model as the total population size tends to infinity. Furth
Age at infection is often an important factor in epidemic dynamics. In this paper a disease transmission model of SIS type with age dependent infection on a heterogeneous network is discussed. The model allows the infectious rate and the recovery rat
In this paper, we analyze dynamic switching networks, wherein the networks switch arbitrarily among a set of topologies. For this class of dynamic networks, we derive an epidemic threshold, considering the SIS epidemic model. First, an epidemic proba
We introduce a nonlinear structured population model with diffusion in the state space. Individuals are structured with respect to a continuous variable which represents a pathogen load. The class of uninfected individuals constitutes a special compa