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Assessing the location and extent of lesions caused by chronic stroke is critical for medical diagnosis, surgical planning, and prognosis. In recent years, with the rapid development of 2D and 3D convolutional neural networks (CNN), the encoder-decoder structure has shown great potential in the field of medical image segmentation. However, the 2D CNN ignores the 3D information of medical images, while the 3D CNN suffers from high computational resource demands. This paper proposes a new architecture called dimension-fusion-UNet (D-UNet), which combines 2D and 3D convolution innovatively in the encoding stage. The proposed architecture achieves a better segmentation performance than 2D networks, while requiring significantly less computation time in comparison to 3D networks. Furthermore, to alleviate the data imbalance issue between positive and negative samples for the network training, we propose a new loss function called Enhance Mixing Loss (EML). This function adds a weighted focal coefficient and combines two traditional loss functions. The proposed method has been tested on the ATLAS dataset and compared to three state-of-the-art methods. The results demonstrate that the proposed method achieves the best quality performance in terms of DSC = 0.5349+0.2763 and precision = 0.6331+0.295).
Segmenting stroke lesions from T1-weighted MR images is of great value for large-scale stroke rehabilitation neuroimaging analyses. Nevertheless, there are great challenges with this task, such as large range of stroke lesion scales and the tissue in
In this work, we propose a new segmentation network by integrating DenseUNet and bidirectional LSTM together with attention mechanism, termed as DA-BDense-UNet. DenseUNet allows learning enough diverse features and enhancing the representative power
Sturge-Weber syndrome (SWS) is a vascular malformation disease, and it may cause blindness if the patients condition is severe. Clinical results show that SWS can be divided into two types based on the characteristics of scleral blood vessels. Theref
Diffusion-weighted (DW) magnetic resonance imaging is essential for the diagnosis and treatment of ischemic stroke. DW images (DWIs) are usually acquired in multi-slice settings where lesion areas in two consecutive 2D slices are highly discontinuous
Recently, a growing interest has been seen in deep learning-based semantic segmentation. UNet, which is one of deep learning networks with an encoder-decoder architecture, is widely used in medical image segmentation. Combining multi-scale features i