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Skin cancer is one of the most common cancers in the United States. As technological advancements are made, algorithmic diagnosis of skin lesions is becoming more important. In this paper, we develop algorithms for segmenting the actual diseased area of skin in a given image of a skin lesion, and for classifying different types of skin lesions pictured in a given image. The cores of the algorithms used were based in persistent homology, an algebraic topology technique that is part of the rising field of Topological Data Analysis (TDA). The segmentation algorithm utilizes a similar concept to persistent homology that captures the robustness of segmented regions. For classification, we design two families of topological features from persistence diagrams---which we refer to as {em persistence statistics} (PS) and {em persistence curves} (PC), and use linear support vector machine as classifiers. We also combined those topological features, PS and PC, into ResNet-101 model, which we call {em TopoResNet-101}, the results show that PS and PC are effective in two folds---improving classification performances and stabilizing the training process. Although convolutional features are the most important learning targets in CNN models, global information of images may be lost in the training process. Because topological features were extracted globally, our results show that the global property of topological features provide additional information to machine learning models.
There has been a steady increase in the incidence of skin cancer worldwide, with a high rate of mortality. Early detection and segmentation of skin lesions are crucial for timely diagnosis and treatment, necessary to improve the survival rate of pati
Deep neural networks (DNNs) have achieved great success in a wide variety of medical image analysis tasks. However, these achievements indispensably rely on the accurately-annotated datasets. If with the noisy-labeled images, the training procedure w
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The segmentation of skin lesions is a crucial task in clinical decision support systems for the computer aided diagnosis of skin lesions. Although deep learning-based approaches have improved segmentation performance, these models are often susceptib
The advances in technology have enabled people to access internet from every part of the world. But to date, access to healthcare in remote areas is sparse. This proposed solution aims to bridge the gap between specialist doctors and patients. This p