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Classifying the various shapes and attributes of a glioma cell nucleus is crucial for diagnosis and understanding the disease. We investigate automated classification of glioma nuclear shapes and visual attributes using Convolutional Neural Networks (CNNs) on pathology images of automatically segmented nuclei. We propose three methods that improve the performance of a previously-developed semi-supervised CNN. First, we propose a method that allows the CNN to focus on the most important part of an image- the images center containing the nucleus. Second, we inject (concatenate) pre-extracted VGG features into an intermediate layer of our Semi-Supervised CNN so that during training, the CNN can learn a set of complementary features. Third, we separate the losses of the two groups of target classes (nuclear shapes and attributes) into a single-label loss and a multi-label loss so that the prior knowledge of inter-label exclusiveness can be incorporated. On a dataset of 2078 images, the proposed methods combined reduce the error rate of attribute and shape classification by 21.54% and 15.07% respectively compared to the existing state-of-the-art method on the same dataset.
Facial Attribute Classification (FAC) has attracted increasing attention in computer vision and pattern recognition. However, state-of-the-art FAC methods perform face detection/alignment and FAC independently. The inherent dependencies between these
We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a WSI, i.e., a
In this paper, we address the problem of image retrieval by learning images representation based on the activations of a Convolutional Neural Network. We present an end-to-end trainable network architecture that exploits a novel multi-scale local poo
We propose a novel approach to enhance the discriminability of Convolutional Neural Networks (CNN). The key idea is to build a tree structure that could progressively learn fine-grained features to distinguish a subset of classes, by learning feature
Fundoscopic images are often investigated by ophthalmologists to spot abnormal lesions to make diagnoses. Recent successes of convolutional neural networks are confined to diagnoses of few diseases without proper localization of lesion. In this paper