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This paper investigates the property of the penalized estimating equations when both the mean and association structures are modelled. To select variables for the mean and association structures sequentially, we propose a hierarchical penalized generalized estimating equations (HPGEE2) approach. The first set of penalized estimating equations is solved for the selection of significant mean parameters. Conditional on the selected mean model, the second set of penalized estimating equations is solved for the selection of significant association parameters. The hierarchical approach is designed to accommodate possible model constraints relating the inclusion of covariates into the mean and the association models. This two-step penalization strategy enjoys a compelling advantage of easing computational burdens compared to solving the two sets of penalized equations simultaneously. HPGEE2 with a smoothly clipped absolute deviation (SCAD) penalty is shown to have the oracle property for the mean and association models. The asymptotic behavior of the penalized estimator under this hierarchical approach is established. An efficient two-stage penalized weighted least square algorithm is developed to implement the proposed method. The empirical performance of the proposed HPGEE2 is demonstrated through Monte-Carlo studies and the analysis of a clinical data set.
We study the existence, strong consistency and asymptotic normality of estimators obtained from estimating functions, that are p-dimensional martingale transforms. The problem is motivated by the analysis of evolutionary clustered data, with distribu
This paper deals with the maximum likelihood estimator for the mean-reverting parameter of a first order autoregressive models with exogenous variables, which are stationary Gaussian noises (Colored noise). Using the method of the Laplace transform,
We study a dimensionality reduction technique for finite mixtures of high-dimensional multivariate response regression models. Both the dimension of the response and the number of predictors are allowed to exceed the sample size. We consider predicto
It is known that there is a dichotomy in the performance of model selectors. Those that are consistent (having the oracle property) do not achieve the asymptotic minimax rate for prediction error. We look at this phenomenon closely, and argue that th
Yang (1978) considered an empirical estimate of the mean residual life function on a fixed finite interval. She proved it to be strongly uniformly consistent and (when appropriately standardized) weakly convergent to a Gaussian process. These results