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Non-monotonic density dependence of the diffusion of DNA fragments in low-salt suspensions

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 نشر من قبل Gerhard Naegele
 تاريخ النشر 2008
  مجال البحث فيزياء
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The high linear charge density of 20-base-pair oligomers of DNA is shown to lead to a striking non-monotonic dependence of the long-time self-diffusion on the concentration of the DNA in low-salt conditions. This generic non-monotonic behavior results from both the strong coupling between the electrostatic and solvent-mediated hydrodynamic interactions, and from the renormalization of these electrostatic interactions at large separations, and specifically from the dominance of the far-field hydrodynamic interactions caused by the strong repulsion between the DNA fragments.

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