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We calculate both the exponential and pre-factor contributions in a WKB approximation of the master equation for a stochastic SIR model with highly oscillatory dynamics. Fixing the basic parameters of the model we investigate how the outbreak distribution changes with the population size. We show that this distribution rapidly becomes highly non-Gaussian, acquiring large tails indicating the presence of rare, but large outbreaks, as the population is made smaller. The analytic results are found to be in excellent agreement with simulations until the systems become so small that the dynamics are dominated by fade-out of the disease.
The COVID-19 pandemic has demonstrated how disruptive emergent disease outbreaks can be and how useful epidemic models are for quantifying risks of local outbreaks. Here we develop an analytical approach to calculate the dynamics and likelihood of ou
Background: A deterministic model is developed for the spatial spread of an epidemic disease in a geographical setting. The disease is borne by vectors to susceptible hosts through criss-cross dynamics. The model is focused on an epidemic outbreak th
In times of outbreaks, an essential requirement for better monitoring is the evaluation of the number of undiagnosed infected individuals. An accurate estimate of this fraction is crucial for the assessment of the situation and the establishment of p
A pandemic caused by a new coronavirus (COVID-19) has spread worldwide, inducing an epidemic still active in Argentina. In this chapter, we present a case study using an SEIR (Susceptible-Exposed-Infected-Recovered) diffusion model of fractional orde
Between pandemics, the influenza virus exhibits periods of incremental evolution via a process known as antigenic drift. This process gives rise to a sequence of strains of the pathogen that are continuously replaced by newer strains, preventing a bu