ترغب بنشر مسار تعليمي؟ اضغط هنا

The availability of a large number of assembled genomes opens the way to study the evolution of syntenic character within a phylogenetic context. The DeCo algorithm, recently introduced by B{e}rard et al. allows the computation of parsimonious evolut ionary scenarios for gene adjacencies, from pairs of reconciled gene trees. Following the approach pioneered by Sturmfels and Pachter, we describe how to modify the DeCo dynamic programming algorithm to identify classes of cost schemes that generates similar parsimonious evolutionary scenarios for gene adjacencies, as well as the robustness to changes to the cost scheme of evolutionary events of the presence or absence of specific ancestral gene adjacencies. We apply our method to six thousands mammalian gene families, and show that computing the robustness to changes to cost schemes provides new and interesting insights on the evolution of gene adjacencies and the DeCo model.
313 - Philippe Rinaudo 2012
We present a general setting for structure-sequence comparison in a large class of RNA structures that unifies and generalizes a number of recent works on specific families on structures. Our approach is based on tree decomposition of structures and gives rises to a general parameterized algorithm, where the exponential part of the complexity depends on the family of structures. For each of the previously studied families, our algorithm has the same complexity as the specific algorithm that had been given before.
357 - Yann Ponty 2012
Two formalisms, both based on context-free grammars, have recently been proposed as a basis for a non-uniform random generation of combinatorial objects. The former, introduced by Denise et al, associates weights with letters, while the latter, recen tly explored by Weinberg et al in the context of random generation, associates weights to transitions. In this short note, we use a simple modification of the Greibach Normal Form transformation algorithm, due to Blum and Koch, to show the equivalent expressivities, in term of their induced distributions, of these two formalisms.
mircosoft-partner

هل ترغب بارسال اشعارات عن اخر التحديثات في شمرا-اكاديميا