Molecular motors transduce chemical energy obtained from hydrolizing ATP into mechanical work exerted against an external force. We calculate their efficiency at maximum power output for two simple generic models and show that the qualitative behavio
ur depends crucially on the position of the transition state. Specifically, we find a transition state near the initial state (sometimes characterized as a power stroke) to be most favorable with respect to both high power output and high efficiency at maximum power. In this regime, driving the motor further out of equilibrium by applying higher chemical potential differences can even, counter-intuitively, increase the efficiency.
For systems in an externally controllable time-dependent potential, the optimal protocol minimizes the mean work spent in a finite-time transition between two given equilibrium states. For overdamped dynamics which ignores inertia effects, the optima
l protocol has been found to involve jumps of the control parameter at the beginning and end of the process. Including the inertia term, we show that this feature not only persists but that even delta peak-like changes of the control parameter at both boundaries make the process optimal. These results are obtained by analyzing two simple paradigmatic cases: First, a Brownian particle dragged by a harmonic optical trap through a viscous fluid and, second, a Brownian particle subject to an optical trap with time-dependent stiffness. These insights could be used to improve free energy calculations via either thermodynamic integration or fast growth methods using Jarzynskis equality.
We study a class of cyclic Brownian heat engines in the framework of finite-time thermodynamics. For infinitely long cycle times, the engine works at the Carnot efficiency limit producing, however, zero power. For the efficiency at maximum power, we
find a universal expression, different from the endoreversible Curzon-Ahlborn efficiency. Our results are illustrated with a simple one-dimensional engine working in and with a time-dependent harmonic potential.
